ArticleAlcoholism, clinical and experimental research2016
Desire to Drink Alcohol is Enhanced with High Caffeine Energy Drink Mixers.
Article in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Alcohol mixed with energy drink (AMED): A critical review and meta-analysis.Human psychopharmacology · 2018Pooled it
- Residual next-day effects of alprazolam on psychomotor performance and simulated driving in healthy normal adults.Experimental and clinical psychopharmacology · 2025Trial
- Faster self-paced rate of drinking for alcohol mixed with energy drinks versus alcohol alone.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017Trial
- No significant gender differences in driving-related skills following alcohol mixed with energy drinks during an experimental binge-drinking episode.Frontiers in pharmacology · 2025Article
- Caffeine consumption and onset of alcohol use among early adolescents.Preventive medicine · 2022Article
- Effects of Caffeine and Caffeinated Beverages in Children, Adolescents and Young Adults: Short Review.International journal of environmental research and public health · 2021Review
- Rewarding and aversive doses of caffeine alter activity but not conditioned place preference induced by ethanol in DBA/2J mice.Pharmacology, biochemistry, and behavior · 2019Article
- Alcohol Mixed with Energy Drinks (AmED) and Negative Alcohol-Related Consequences among South Korean College Students.International journal of environmental research and public health · 2019Article
- Intensity of Energy Drink Use Plus Alcohol Predict Risky Health Behaviours among University Students in the Caribbean.International journal of environmental research and public health · 2018Article
- Alcohol mixed with energy drink use during young adulthood.Addictive behaviors · 2018Article
- Differential development of acute tolerance may explain heightened rates of impaired driving after consumption of alcohol mixed with energy drinks versus alcohol alone.Experimental and clinical psychopharmacology · 2018Article
- Alcohol-Induced Impairment of Balance is Antagonized by Energy Drinks.Alcoholism, clinical and experimental research · 2018Article
- Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain.Birth defects research · 2017Review
- Intoxication-Related Alcohol Mixed with Energy Drink Expectancies Scale: Initial Development and Validation.Alcoholism, clinical and experimental research · 2017Article
- Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings.Psychopharmacology · 2017Article
- The Safety of Ingested Caffeine: A Comprehensive Review.Frontiers in psychiatry · 2017Review
- Supplemental taurine during adolescence and early adulthood has sex-specific effects on cognition, behavior and neurotransmitter levels in C57BL/6J mice dependent on exposure window.Neurotoxicology and teratologyArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundConsumption of alcohol mixed with energy drinks (AmED) has been associated with a variety of risks beyond that observed with alcohol alone. Consumers of AmED beverages are more likely to engage in heavy episodic (binge) drinking. This study was to investigate whether the consumption of high caffeine energy drink mixers with alcohol would increase the desire to drink alcohol compared to the same amount of alcohol alone using a double-blind, within-subjects, placebo-controlled study design.
methodsParticipants (n = 26) of equal gender who were social drinkers attended 6 double-blind dose administration sessions that involved consumption of alcohol and energy drinks, alone and in combination. On each test day, participants received 1 of 6 possible doses: (i) 1.21 ml/kg vodka + 3.63 ml/kg decaffeinated soft drink, (ii) 1.21 ml/kg vodka + 3.63 ml/kg energy drink, (iii) 1.21 ml/kg vodka + 6.05 ml/kg energy drink, (iv) 3.63 ml/kg decaffeinated soft drink, (v) 3.63 ml/kg energy drink, and (vi) 6.05 ml/kg energy drink. Following dose administration, participants repeatedly completed self-reported ratings on the Desire-for-Drug questionnaire and provided breath alcohol readings.
resultsAlcohol alone increased the subjective ratings of "desire for more alcohol" compared to placebo doses. Energy drink mixers with the alcohol increased desire for more alcohol ratings beyond that observed with alcohol alone.
conclusionsThis study provides laboratory evidence that AmED beverages lead to greater desire to drink alcohol versus the same amount of alcohol consumed alone. The findings are consistent with results from animal studies indicating that caffeine increases the rewarding and reinforcing properties of alcohol.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.