Evidence map›Paper›PMID 27419089›Full record

ArticleJournal of traditional and complementary medicine2016

Effect of Shin'iseihaito on murine allergic reaction induced by nasal sensitization.

Masaaki Minami, Toru Konishi, Zhixia Jiang, Tetsuya Arai, Toshiaki Makino

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. The Protective Role ofInternational journal of molecular sciences · 2024
    Article
  3. Pulmonary sarcoidosis with lung injury induced by shin'iseihaito.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2022
    Article
  4. Article
  5. Anti-anaphylactic and antiasthmatic activity ofJournal of traditional and complementary medicine · 2019
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Effect of Shin'iseihaito (Xinyiqingfeitang) on AcuteEvidence-based complementary and alternative medicine : eCAM · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masaaki MinamiDepartment of Bacteriology, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-ku, Nagoya, Japan.
Toru KonishiDepartment of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-Dori, Mizuho-ku, Nagoya, Japan.
Zhixia JiangR&D Center, Kobayashi Pharmaceutical Co., Ltd., 4-10 Doshomachi 4-chome, Chuo-ku, Osaka, Japan.
Tetsuya AraiR&D Center, Kobayashi Pharmaceutical Co., Ltd., 4-10 Doshomachi 4-chome, Chuo-ku, Osaka, Japan.
Toshiaki MakinoDepartment of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-Dori, Mizuho-ku, Nagoya, Japan.
Nagoya City University · JPKobayashi Pharmaceutical (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shin'iseihaito (Magnolia Flower Lung-Clearing Decoction; xīn yí qīng fèi tāng), a formula of traditional Japanese kampo medicine ( rì běn hàn yī) and traditional Chinese medicine (TCM; zhōng yī), has been used for the treatment of chronic sinusitis. The objective of this study was to evaluate the anti-allergic effect of shin'iseihaito on murine allergic reaction induced by nasal sensitization using ovalbumin (OVA) as an antigen. Extract of shin'iseihaito (SSHT) could reduce the eosinophil, serum IgE and interleukin (IL)-4 levels, while increased the interferon (IFN)-γ levels in allergic mouse. Furthermore, allergic-murine serum treated with SSHT could not activate passive cutaneous anaphylaxis (PCA) reaction in murine model. Thus, our study showed that SSHT may possess anti-allergic activity. We suggested that SSHT may contribute to inhibit the exacerbation of allergic reaction induced by nasal sensitization.

Indexed as

IgEInterferon-γInterleukin-4Passive cutaneous anaphylaxis reactionShin'iseihaito

Identifiers

PMID27419089
PMCPMC4936765
OpenAlexW845504823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.