Evidence map›Paper›PMID 27418934›Full record

ArticleInternational journal of pediatrics2016

Fecal Microbiota and Diet of Children with Chronic Constipation.

Joyce Gomes de Moraes, Maria Eugênia Farias de Almeida Motta, Monique Ferraz de Sá Beltrão, Taciana Lima Salviano, Giselia Alves Pontes da Silva

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05318365 (Bladder and Bowel Dysfunction in Children), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05318365 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Bladder and Bowel Dysfunction in Children

TypeinterventionalSponsorUniversity of AarhusRan2022 to 2025Enrolled100ConditionsBladder and Bowel DysfunctionArmsPolyethylene Glycol 3350, Urotherapy
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. GUT MICROBIOTA AND THE USE OF PROBIOTICS IN CONSTIPATION IN CHILDREN AND ADOLESCENTS: SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joyce Gomes de MoraesFederal University of Pernambuco, Avenida Professor Moraes Rego 1235, University City, 50670-901 Recife, PE, Brazil.ORCID 0000-0003-2222-6185
Maria Eugênia Farias de Almeida MottaMother-Child Department, Federal University of Pernambuco, Avenida Professor Moraes Rego 1235, University City, 50670-901 Recife, PE, Brazil.
Monique Ferraz de Sá BeltrãoDepartment of Biotechnology, Laboratory of Immunopathology Keizo Asami (LIKA), Avenida Professor Moraes Rego 1235, University City, 50670-901 Recife, PE, Brazil.
Taciana Lima SalvianoDepartment of Biotechnology, Laboratory of Immunopathology Keizo Asami (LIKA), Avenida Professor Moraes Rego 1235, University City, 50670-901 Recife, PE, Brazil.
Giselia Alves Pontes da SilvaMother-Child Department, Federal University of Pernambuco, Avenida Professor Moraes Rego 1235, University City, 50670-901 Recife, PE, Brazil.ORCID 0000-0002-5310-3420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many factors explain dysbiosis in chronic constipation (CC), such as a low-fiber diet. The objective of this study was to compare the fecal microbiota of constipated and nonconstipated children and their intake frequencies of food. Methods. This observational study included 79 children (M/F 43/36) aged six to 36 months divided into two groups: cases (39 constipated children) and controls (40 nonconstipated children). We used a structured form to collect demographic variables, conducted anthropometric assessment, and collected food intake frequency data. The fecal microbiota of the stool samples was analyzed by real-time polymerase chain reaction (PCR) using the fluorophore SYBR® Green. Results. Constipated children had a smaller concentration of Lactobacillus per milligram of stool (p = 0.015) than nonconstipated children, but the concentration of Bifidobacterium per milligram of stool (p = 0.323) and the intake of fruits, vegetables (p = 0.563), and junk food (p = 0.093) of the two groups did not differ. Constipated children consumed more dairy products (0.45 ± 0.8; p > 0.001), were more frequently delivered via caesarean section (69.2%), were weaned earlier (median: 120; 60Q1-240Q3), and had a family history of constipation (71.8%). Conclusions. Children with CC have a smaller concentration of Lactobacillus in their stools and consume more dairy products.

Identifiers

PMID27418934
PMCPMC4935906

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.