Evidence map›Paper›PMID 27418883›Full record

Trial reportJournal of the International Society of Sports Nutrition2016

Branched-chain amino acids, arginine, citrulline alleviate central fatigue after 3 simulated matches in taekwondo athletes: a randomized controlled trial.

I-Fan Chen, Huey-June Wu, Chung-Yu Chen, Kuei-Ming Chou, Chen-Kang Chang

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
11.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  18. Recovery Methods in Basketball: A Systematic Review.Sports (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

I-Fan ChenGraduate Institute of Sport Coaching Science, Chinese Culture University, 55, Huagang Rd, Shilin District Taipei, 111 Taiwan.
Huey-June WuGraduate Institute of Sport Coaching Science, Chinese Culture University, 55, Huagang Rd, Shilin District Taipei, 111 Taiwan.
Chung-Yu ChenDepartment of Physical Education, National Taiwan University of Sport, 16, Sec 1, Shuan-Shih Rd, Taichung, 404 Taiwan.
Kuei-Ming ChouDepartment of Combat Sport, National Taiwan University of Sport, 16, Sec 1, Shuan-Shih Rd, Taichung, 404 Taiwan.
Chen-Kang ChangSport Science Research Center, National Taiwan University of Sport, 16, Sec 1, Shuan-Shih Rd, Taichung, 404 Taiwan.ORCID 0000-0001-8335-6595
National Taiwan University of Sport · TWChinese Culture University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe decline in cognitive performance has been shown after fatiguing exercise. Branched-chain amino acids (BCAA) have been suggested to alleviate exercise-induced central fatigue. Arginine and citrulline could remove the excess NH3 accumulation accompanied with BCAA supplementation by increasing nitric oxide biosynthesis and/or urea cycle. The purpose of this study is to investigate the effect of the combined supplementation of BCAA, arginine, and citrulline on central fatigue after three simulated matches in well-trained taekwondo athletes.

methodsIn a double-blind randomized cross-over design, 12 male taekwondo athletes performed two trials containing three simulated matches each. Each match contained three 2-min rounds of high-intensity intermittent exercise. At the end of the second match, two different supplementations were consumed. In the AA trial, the subjects ingested 0.17 g/kg BCAA, 0.05 g/kg arginine and 0.05 g/kg citrulline, while placebo was consumed in the PL trial. A validated taekwondo-specific reaction test battery was used to measure the cognitive performance after each match.

resultsThe premotor reaction time in the three single-task tests and the reaction time in the secondary task in the dual-task test were maintained in the AA trial after three matches, while they were impaired in the PL trial, resulting in significantly better performance in the AA trial. These improvements in the AA trial coincided with significantly lower plasma free tryptophan/BCAA ratio, increased NOx concentrations, and similar NH3 concentrations.

conclusionsThis study suggested that the combined supplementation could alleviate the exercise-induced central fatigue in elite athletes.

Indexed as

AthletesAmino Acids, Branched-ChainArginineAthletic PerformanceCitrullineCross-Over StudiesDietary SupplementsDouble-Blind MethodExercise TestHumansMaleMartial ArtsMuscle FatiguePhysical EnduranceSports Nutritional Physiological PhenomenaTaiwanAmino Acids, Branched-ChainArginineCitrullineDual taskPremotor reaction timeTaekwondoTryptophan

Identifiers

PMID27418883
PMCPMC4944315
OpenAlexW2463504128

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.