ArticleTherapeutics and clinical risk management2016
The Oxfordshire Community Stroke Project classification system predicts clinical outcomes following intravenous thrombolysis: a prospective cohort study.
Article in Therapeutics and clinical risk management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Current Trends in Stroke Biomarkers: The Prognostic Role of S100 Calcium-Binding Protein B and Glial Fibrillary Acidic Protein.Life (Basel, Switzerland) · 2024Review
- Insights into Iron Metabolism Parameters in Ischemic Stroke: A Single-Center Prospective Cohort Study.International journal of molecular sciences · 2024Article
- Article
- Neuron-specific enolase as a prognostic biomarker in acute ischemic stroke patients treated with reperfusion therapies.Frontiers in neurology · 2024Article
- Clinical and Imaging Phenotypes and Outcomes in a Costa Rican Cohort of Acute Ischemic Stroke Survivors: A Retrospective Study.Journal of clinical medicine · 2023Article
- Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Observational
- The Diagnostic Value of Whole Blood lncRNA NR_120420 for Acute Ischemic Stroke.Oxidative medicine and cellular longevity · 2022Article
- Oxfordshire Community Stroke Project Classification: A proposed automated algorithm.European stroke journal · 2021Article
- Ischemic Stroke Subtypes: Socio-demographic Factors, Risk Factors, and Outcomes in Southern Sri Lanka.Ethnicity & disease · 2021Article
- Analysis of Prognostic Risk Factors Determining Poor Functional Recovery After Comprehensive Rehabilitation Including Motor-Imagery Brain-Computer Interface Training in Stroke Patients: A Prospective Study.Frontiers in neurology · 2021Article
- Association between serum non-high-density lipoprotein cholesterol and cognitive dysfunction after acute ischemic stroke: a cross-sectional study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Article
- Recurrent thrombolysis of a stuttering lacunar infarction captured on serial MRIs.eNeurologicalSci · 2018Article
- Plasma MicroRNA-16 Is a Biomarker for Diagnosis, Stratification, and Prognosis of Hyperacute Cerebral Infarction.PloS one · 2016Article
- The Pitfalls of NIHSS: Time for a New Clinical Acute Stroke Severity Scoring System in the Emergency?Annals of Indian Academy of NeurologyArticle
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9 authors.
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Abstract
backgroundThe Oxfordshire Community Stroke Project (OCSP) classification system is a simple stroke classification system that can be used to predict clinical outcomes. In this study, we compare the safety and efficacy of intravenous thrombolysis in Chinese stroke patients categorized using the OCSP classification system. PATIENTS AND
methodsWe collected data from the Thrombolysis Implementation and Monitoring of Acute Ischemic Stroke in China registry. A total of 1,115 patients treated with intravenous thrombolysis with alteplase within 4.5 hours of stroke onset were included. Symptomatic intracranial hemorrhage (SICH), mortality, and 90-day functional outcomes were compared between the stroke patients with different stroke subtypes.
resultsOf the 1,115 patients included in the cohort, 197 (17.67%) were classified with total anterior circulation infarct (TACI), 700 (62.78%) with partial anterior circulation infarct, 153 (13.72%) with posterior circulation infarct, and 65 (5.83%) with lacunar infarct. After multivariable adjustment, compared to the patients with non-TACI, those with TACI had a significantly increased risk of SICH (odds ratio [OR] 8.80; 95% confidence interval [CI] 2.84-27.25, P<0.001), higher mortality (OR 5.24; 95% CI 3.19-8.62; P<0.001), and poor functional independence (OR 0.38; 95% CI 0.26-0.56; P<0.001) at 3-month follow-up.
conclusionAfter thrombolysis, the patients with TACI exhibited greater SICH, a higher mortality rate, and worse 3-month clinical outcomes compared with the patients with non-TACI. The OCSP classification system may help clinicians predict the safety and efficacy of thrombolysis.
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