ArticleHippokratia
The Patient State Index is well balanced for propofol sedation.
Article in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Remimazolam-remifentanil causes less postoperative nausea and vomiting than remimazolam-alfentanil during hysteroscopy: a single-centre randomized controlled trial.BMC anesthesiology · 2023Trial
- Difficulty Controlling Sedation Level Using Processed Electroencephalography Monitoring in a Patient With Intellectual Disability, Fontan Circulation, and a Severe Gag Reflex.Anesthesia progress · 2025Article
- Assessment of recovery in maxillofacial surgical patients undergoing intravenous conscious sedation using PSI monitoring.Oral and maxillofacial surgery · 2025Article
- Intraoperative cardiac arrest caused by unexpected vasospastic angina requiring prolonged resuscitation using extracorporeal membrane oxygenation: a case report.JA clinical reports · 2023Article
- Efficacy and safety of remimazolam besilate for sedation in outpatients undergoing impacted third molar extraction: a prospective exploratory study.BMC oral health · 2023Article
- Time-trend analysis of the center frequency of the intrinsic mode function from the Hilbert-Huang transform of electroencephalography during general anesthesia: a retrospective observational study.BMC anesthesiology · 2023Observational
- Effect of sevoflurane-remifentanil and propofol-remifentanil anesthesia on glycocalyx shedding during deep inferior epigastric perforator flap breast reconstruction: a prospective randomized, controlled trial.Anesthesia and pain medicine · 2023Article
- Usability of the SedLine® electroencephalographic monitor of depth of anaesthesia in pigs: a pilot study.Journal of clinical monitoring and computing · 2022Article
- Electroencephalogram-Based Evaluation of Impaired Sedation in Patients with Moderate to Severe COVID-19 ARDS.Journal of clinical medicine · 2022Article
- Normative values for SedLine-based processed electroencephalography parameters in awake volunteers: a prospective observational study.Journal of clinical monitoring and computing · 2021Observational
- Case Report: Ultrasound Sciatic and Saphenous Nerve Blocks for Tibial Malunion Surgical Correction in a Pediatric African Leopard (Frontiers in veterinary science · 2020Article
- Comparison of Two Methods of Anesthesia Using Patient State Index: Propofol Versus Sevoflurane During Interventional Neuroradiology Procedure.Anesthesiology and pain medicine · 2019Article
- Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram.British journal of anaesthesia · 2017Observational
- Comparison between patient state index, bispectral index, and clinical parameters for propofol induction in Indian patients: A prospective study.Journal of anaesthesiology, clinical pharmacologyArticle
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Authors and funding
4 authors.
Funding
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Abstract
backgroundThe SEDLine™ monitor derived patient state index (PSI) is used to follow the depth of sedation. The demand for propofol sedation by anesthesiologists or non-anesthesiologists is increasing, and there are only a few studies addressing the relationship between PSI and propofol sedation. We aimed to investigate the ability of PSI index to identify the correct level of sedation of our patients during induction to anesthesia with target-controlled infusions of propofol.
methodsTwenty patients were enrolled in this study. The target effect site concentration of propofol was set at 1.5 μg/ml followed by increments of 0.5 μg/ml every five minutes. The PSI values and Modified Observer's Assessment of Alertness/Sedation (MOAA/S) scale were recorded every twenty-five seconds during the infusion of propofol. Patients were considered losing verbal responsiveness at MOAA/S scale ≤ 2. Also, blood pressure, heart rate, and oxygen saturation were recorded every five minutes.
resultsThe PSI values corresponding to the sedation of various depths (MOAA/S scales) and alertness with verbal response were significantly different (p <0.001). We observed a good correlation of the PSI values to the decreasing MOAA/S scale (r =0.87667).
conclusionsThe PSI index is well correlated with MOAA/S scale and effectively distinguishes the level of sedation during propofol infusion. Hippokratia 2015; 19 (3): 235-238.
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27418783PMC4938471What OpenQuestion holds
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