Evidence map›Paper›PMID 27418766›Full record

ArticleHippokratia

Dynamic changes of carotid artery intima-media thickness and mortality in hemodialysis patients.

R Stolic, A Ilic, A Jovanovic, R Grbic, D Odalovic, Lj Smilic, S Lazic, B Krdzic, J Nedovic

Open access · greenAbstract read
In one paragraph

Article in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

R StolicClinic of Nephrology and Urology, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
A IlicInstitute of Medical Statistics and Informatics, University of Kragujevac, Kragujevac, Serbia.
A JovanovicInternal Medicine Department, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
R GrbicDepartment of Orthopedics, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
D OdalovicChildren's Hospital, Faculty of Medicine Pristina/Kosovska Mitrovica, University of Pristina, Serbia.
Lj SmilicInternal Medicine Department, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
S LazicInternal Medicine Department, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
B KrdzicInternal Medicine Department, Medical faculty, University of Kragujevac, Kragujevac, Serbia.
J NedovicDepartment of Radiology and Oncology, Clinical Center Kragujevac, Serbia.
University of Kragujevac · RSClinical Centre of Kragujevac · RSUniversity of Prishtina · XK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntima-media thickness (IMT) of the carotid artery is a widely accepted parameter for detection and quantification of atherosclerosis. The aim of the study was the evaluation of the impact of changes of IMT on the mortality of patients on hemodialysis.

methodsThe study was organized as a prospective and observational one. Intima-media thickness was determined by ultrasound in 194 patients who were evaluated every year during a three-year period. We analyzed the mortality rate of patients on hemodialysis in relation to their biochemical parameters, demographic and anthropometric characteristics, type of dialysis, smoking habits and statin therapy.

resultsFemale gender and hemodiafiltration emerged as good predictors of long-term survival. Baseline IMT values were significantly lower than those at the end of the second (p <0.001) and third years of the study (p <0.001). The baseline values positively correlated with uric acid levels (p =0.027) and body mass index (p =0.024), while at the end of the second year, IMT positively correlated with LDL-cholesterol (p =0.037) and triglyceride levels (p =0.018) and body mass index (p =0.045). Patients on hemodiafiltration had significantly higher values for erythrocytes (p =0.047), hemoglobin (p =0.005), creatinine (p =0.048), Kt/V (p =0.026), albumin (p =0.012), LDL-cholesterol (p <0.001), body mass index (p <0.001),and lower IMT values at the end of the first year (p =0.039), compared to patients on bicarbonate hemodialysis. Predictors of death were the duration of hemodialysis (p <0.001), and IMT at the end of the first (p =0.008) and second years of the study (p =0.005).

conclusionDynamic changes of IMT of the carotid arteries during the first two years were found in our study to be predictors of mortality in patients on hemodialysis. Hippokratia 2015; 19 (2):158-163.

Indexed as

atherogenesiscarotid intima mediaDynamic changeshemodialysismortality

Identifiers

PMID27418766
PMCPMC4938108
OpenAlexW2507947304

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.