ReviewHippokratia
The relationship of stress and blood pressure effectors.
Review in Hippokratia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Impact of Electrical Stimulation on Mental Stress, Depression, and Anxiety: A Systematic Review.Sensors (Basel, Switzerland) · 2025Pooled it
- Does Reiki Benefit Mental Health Symptoms Above Placebo?Frontiers in psychology · 2022Pooled it
- Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis.BMC complementary medicine and therapies · 2021Pooled it
- A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.Advances in therapy · 2025Trial
- Effect of aromatherapy with lemongrass (Cymbopogon citratus) on the anxiety of patients undergoing scaling and root planning: a randomized clinical trial.BMC complementary medicine and therapies · 2025Trial
- Biophilic classroom environments on stress and cognitive performance: A randomized crossover study in virtual reality (VR).PloS one · 2023Trial
- Trial
- Hemodynamic impact of increasing time between fentanyl and propofol administration during anesthesia induction: a randomised, clinical trial.Brazilian journal of anesthesiology (Elsevier)Trial
- Health-related factors and epigenetic alterations in metabolic comorbidities patients and smokers with carpal tunnel syndrome: a preliminary investigation of patient-derived samples.Journal of orthopaedic surgery and research · 2026Article
- CO and NPflugers Archiv : European journal of physiology · 2026Article
- Domain-Specific Paradox of Physical Activity and Depression Among Patients With Cardiovascular Disease or Related Conditions.Journal of the American Heart Association · 2026Article
- Genetic polymorphisms in cardiovascular disease susceptibility among different ethnic groups.Bioinformation · 2026Article
- Barriers to Blood Pressure Control in Treated Patients Attending Public Primary Healthcare Clinics in Gaborone, Botswana.Public health challenges · 2025Article
- The relationship between blood pressure and cognitive decline differs by race.The Gerontologist · 2025Article
- Modern Smart Gadgets and Wearables for Diagnosis and Management of Stress, Wellness, and Anxiety: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2025Review
- Psychological stress among hypertensive male patients in Jordan: prevalence and associated factors.BMC public health · 2024Article
- Metabolic Syndrome as a Risk Factor Among Lebanese Patients with Substance Use Disorder Undergoing Treatment for Recovery Through Rehabilitation or Opioid Substitution Treatment.Clinics and practice · 2024Article
- Cardiovascular and Ocular Parameter Alterations in Response to Cold Pressor Test in Young Adults.Diagnostics (Basel, Switzerland) · 2024Article
- The Effect of Stress-Reducing Interventions on Heart Rate Variability in Cardiovascular Disease: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2024Review
- Role and Status of Biomarkers in Technostress Research: A Systematic Review.Psychology research and behavior management · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exaggerated cardiovascular response to acute and chronic stresses increases the risk for hypertension and cardiovascular disease. Stress also can be broadly defined as a disruption of homeostasis. The re-establishment and maintenance of homeostasis entail the coordinated activation and control of neuroendocrine and autonomic stress systems. Stressor-related information from all major sensory systems is conveyed to the brain. Brain activates neural and neuroendocrine systems to minimize the harmful effects of stress. Stress is generally thought to contribute to the development of hypertension. On the other hand, the evidence is still inconclusive. It is generally accepted that stress-induced hypertension occurs because of increases in sympathoadrenal activity, which enhances vascular tone, but complete α-adrenoreceptor blockade cannot prevent the long-lasting vasoconstriction induced by sympathetic nerve stimulation. That is why it is suggested that sympathetic nerve-mediated vasoconstriction may also be mediated by factors other than catecholamines. In this review, we aim to present the relationship between blood pressure effectors and stress altogether, along with evaluating the relationship between stress and blood pressure. In this respect, we have identified topics to explain the relationship between stress and the renin angiotensin aldosterone system, glucocorticoids, endothelial nitric oxide, endothelin-1 and L-type Ca2+ channels. Hippokratia 2015; 19 (2): 99-108.
Indexed as
Identifiers
27418756PMC4938117W2515167107What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.