ArticleAJNR. American journal of neuroradiology2016
Diffusion Tensor Imaging of the Normal Cervical and Thoracic Pediatric Spinal Cord.
Article in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Spatial scale of indentation explains shift in ratio between spinal cord gray and white matter stiffness.Scientific reports · 2026Article
- Tract-specific analysis of diffusion MRI at 3T detects cervical spinal cord aberrations in multiple sclerosis.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A matched case-control study of early cervical spondylotic myelopathy based on diffusion magnetic resonance imaging.Insights into imaging · 2024Article
- Correlations of diffusion tensor imaging and clinical measures with spinal cord cross-sectional area measurements in pediatric spinal cord injury patients.The journal of spinal cord medicine · 2023Article
- Porcine Model of the Growing Spinal Cord-Changes in Diffusion Tensor Imaging Parameters.Animals : an open access journal from MDPI · 2023Article
- Variation in Diffusion Tensor Imaging Parameters in the Cervical and Thoracic Spinal Cord (C1-C5 and C6-T2) Segments of Normal Beagle Dogs.Veterinary sciences · 2023Article
- Clinical Utility of Diffusion Tensor Imaging as a Biomarker to Identify Microstructural Changes in Pediatric Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2022Article
- Diffusion Kurtosis Imaging of Neonatal Spinal Cord in Clinical Routine.Frontiers in radiology · 2022Article
- Atlas-Based Quantification of DTI Measures in a Typically Developing Pediatric Spinal Cord.AJNR. American journal of neuroradiology · 2021Article
- Specific microstructural changes of the cervical spinal cord in syringomyelia estimated by diffusion tensor imaging.Scientific reports · 2021Article
- Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review.Frontiers in human neuroscience · 2021Review
- Magnetization transfer and diffusion tensor imaging in dogs with intervertebral disk herniation.Journal of veterinary internal medicine · 2020Article
- Quantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient Population.AJNR. American journal of neuroradiology · 2019Article
- Diffusion Tensor Imaging Assessment of Regional White Matter Changes in the Cervical and Thoracic Spinal Cord in Pediatric Subjects.Journal of neurotrauma · 2019Article
- Diffusion tensor imaging (DTI) and Tractography of the spinal cord in pediatric population with spinal lipomas: preliminary study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Predictive value of flexion and extension diffusion tensor imaging in the early stage of cervical myelopathy.Neuroradiology · 2018Article
- Zonally Magnified Oblique Multislice and Non-Zonally Magnified Oblique Multislice DWI of the Cervical Spinal Cord.AJNR. American journal of neuroradiology · 2018Article
- Reduced Field of View Diffusion Tensor Imaging and Fiber Tractography of the Pediatric Cervical and Thoracic Spinal Cord Injury.Journal of neurotrauma · 2018Article
- Characterization of spinal cord diffusion tensor imaging metrics in clinically asymptomatic pediatric subjects with incidental congenital lesions.Spinal cord series and cases · 2018Article
- Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord.NeuroImage. Clinical · 2018Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
background and purposeDTI data of the normal healthy spinal cord in children are limited compared with adults and are typically focused on the cervical spinal cord. The purpose of this study was the following: to investigate the feasibility of obtaining repeatable DTI parameters along the entire cervical and thoracic spinal cord as a function of age in typically developing pediatric subjects; to analyze the DTI parameters among different transverse levels of the cervical and thoracic spinal cord; and to examine the sex differences in DTI parameters along the cervical and thoracic spinal cord. MATERIALS AND
methodsTwenty-two subjects underwent 2 identical scans by using a 3T MR imaging scanner. Axial diffusion tensor images were acquired by using 2 overlapping slabs to cover the cervical and thoracic spinal cord. After postprocessing, DTI parameters were calculated by using ROIs drawn on the whole cord along the entire spinal cord for both scans.
resultsAn increase in fractional anisotropy and a decrease in mean diffusivity, axial diffusivity, and radial diffusivity were observed with age along the entire spinal cord. Significantly lower fractional anisotropy and higher mean diffusivity values were observed in the lower cervical cord compared with the upper cervical cord. Axial diffusivity values in the cervical cord were higher compared with the thoracic cord. No statistically significant sex differences were observed for all DTI parameters. There was a moderate-to-strong repeatability for all DTI parameters.
conclusionsThis study provides an initial understanding of DTI values of the spinal cord relevant to age and sex and shows that obtaining repeatable DTI values of the entire cord in children is feasible.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.