Evidence map›Paper›PMID 27418360›Full record

ReviewApplied microbiology and biotechnology2016

Insect antimicrobial peptides: potential tools for the prevention of skin cancer.

Miray Tonk, Andreas Vilcinskas, Mohammad Rahnamaeian

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. CancerPPD2: an updated repository of anticancer peptides and proteins.Database : the journal of biological databases and curation · 2025
    Article
  3. The Contribution of Human Antimicrobial Peptides to Fungi.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Peptide Fractions Extracted from the Hemolymph ofInternational journal of molecular sciences · 2025
    Article
  6. Biological Activity of Peptide Fraction Derived fromInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Insects · 2023
    Article
  10. Unraveling the Role of Antimicrobial Peptides in Insects.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Frontiers in oncology · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Itch in Hymenoptera Sting Reactions.Frontiers in allergy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Miray TonkLOEWE Center for Insect Biotechnology and Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse, 35394, Giessen, Germany.
Andreas VilcinskasLOEWE Center for Insect Biotechnology and Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse, 35394, Giessen, Germany.
Mohammad RahnamaeianLOEWE Center for Insect Biotechnology and Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse, 35394, Giessen, Germany. mohammad.rahnamaeian@uni-giessen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides/proteins (AMPs) are biologically active molecules with diverse structural properties that are produced by mammals, plants, insects, ticks, and microorganisms. They have a range of antibacterial, antifungal, antiviral, and even anticancer activities, and their biological properties could therefore be exploited for therapeutic and prophylactic applications. Cancer and cancer drug resistance are significant current health challenges, so the development of innovative cancer drugs with minimal toxicity toward normal cells and novel modes of action that can evade resistance may provide a new direction for anticancer therapy. The skin is the first line of defense against heat, sunlight, injury, and infection, and skin cancer is thus the most common type of cancer. The skin that has been exposed to sunlight is particularly susceptible, but lesions can occur anywhere on the body. Skin cancer awareness and self-efficacy are necessary to improve sun protection behavior, but more effective preventative approaches are also required. AMPs may offer a new prophylactic approach against skin cancer. In this mini review, we draw attention to the potential use of insect AMPs for the prevention and treatment of skin cancer.

Indexed as

AnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsHumansInsectaInsect ProteinsSkin NeoplasmsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsInsect ProteinsAntimicrobial peptidesCosmetic industryProphylaxisSkin cancerSun cream

Identifiers

PMID27418360
PMCPMC4980408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.