ArticleScientific reports2016
Mitogenomic perspectives on the origin of Tibetan loaches and their adaptation to high altitude.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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68 citing papers in PubMed, 150 citations in OpenAlex.
- Article
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- Rapid speciation of Chinese hypogean fishes driven by paleogeoclimatic and morphological adaptations.Current zoology · 2025Article
- A Splicing Mutation in mitfa is Involved in the Depigmentation of Cavefish Triplophysa rosa.Molecular biology and evolution · 2025Article
- Effects of Habitat Differences and Invasive Species Competition on Age and Growth ofAnimals : an open access journal from MDPI · 2025Article
- Morphological and Histological Analysis of the Gastrointestinal Systems inAnimals : an open access journal from MDPI · 2025Article
- Mitochondrial Genomes of SixEcology and evolution · 2025Article
- Whole-genome relaxed selection and molecular constraints in Triplophysa under adapted Qinghai-Tibetan Plateau.BMC genomics · 2025Article
- Terrestrial Adaptation inGenes · 2025Article
- Complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2025Article
- Characterization and phylogenetic implications of newly sequenced mitochondrial genomes of cobitid fish Acantopsis Rungthipae (Boyd, Nithirojpakdee & Page, 2017).Molecular biology reports · 2024Article
- Effect of locomotor preference on the evolution of mitochondrial genes in Bovidae.Scientific reports · 2024Article
- Mitochondrial Genomic Evidence of Selective Constraints in Small-Bodied Terrestrial Cetartiodactyla.Animals : an open access journal from MDPI · 2024Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Tibetan loaches are the largest group of Tibetan fishes and are well adapted to the Tibetan Plateau. To investigate the origin of Tibetan loaches and their adaptations to the Tibetan Plateau, we determined 32 complete mitochondrial genomes that included 29 Tibetan loach species, two Barbatula species and Schistura longus. By combining these newly determined sequences with other previously published mitochondrial genomes, we assembled a large mitogenomic data set (11,433 bp) of 96 species in the superfamily Cobitoidea, to investigate the phylogenetic status of the genus Triplophysa. The resulting phylogeny strongly supported that the genus Triplophysa forms a monophyletic group within Nemacheilidae. Our molecular dating time suggests that the lineage leading to the Tibetan loaches and other loaches diverged approximately 23.5 Ma, which falls within the period of recent major uplifts of the Tibetan Plateau in the Early Miocene. Selection analyses revealed that the mitochondrial protein-coding genes of Tibetan loaches have larger ratios of nonsynonymous to synonymous substitutions than do those of non-Tibetan loaches, indicating that Tibetan loaches accumulated more nonsynonymous mutations than non-Tibetan loaches and exhibited rapid evolution. Two positively selected sites were identified in the ATP8 and ND1 genes.
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