Evidence map›Paper›PMID 27417953›Full record

ArticleJournal of comparative effectiveness research2016

Physicians' perspectives regarding pragmatic clinical trials.

Rachel Topazian, Juli Bollinger, Kevin P Weinfurt, Rachel Dvoskin, Debra Mathews, Kathleen Brelsford, Matthew DeCamp, Jeremy Sugarman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of comparative effectiveness research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Do Clinicians Have a Duty to Participate in Pragmatic Clinical Trials?The American journal of bioethics : AJOB · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel TopazianBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
Juli BollingerBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
Kevin P WeinfurtDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
Rachel DvoskinBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
Debra MathewsBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
Kathleen BrelsfordDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
Matthew DeCampBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.
Jeremy SugarmanBerman Institute of Bioethics, Johns Hopkins University, Baltimore, MD, USA.

Funding

Health Care Systems Research Collaboratory SupplementU54AT007748 · NCCIH · DUKE UNIVERSITY · PI CURTIS, LESLEY H, HERNANDEZ, ADRIAN · 2012 to 2017
$15.1M
NCCIH NIH HHS U54 AT007748
6 · The paper itself

Abstract

aimPracticing physicians inevitably become involved in pragmatic clinical trials (PCTs), including comparative effectiveness research. We sought to identify physicians' perspectives related to PCTs.

methodsIn-depth semistructured interviews with 20 physicians in the USA.

resultsAlthough physicians are generally willing to participate in PCTs, their support is predicated on several factors including expected benefits, minimization of time and workflow burdens and physician engagement. Physicians communicated a desire to respect patients' rights and interests while maintaining a high level of care.

conclusionFuture work is needed to systematically assess the impact of PCTs on clinicians in meeting their ethical obligations to patients and the burdens clinicians are willing to accept in exchange for potential benefits.

Indexed as

Attitude of Health PersonnelPhysiciansPragmatic Clinical Trials as TopicComparative Effectiveness ResearchHumanscomparative effectiveness researchethicsqualitative research

Identifiers

PMID27417953
PMCPMC4975022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.