Observational studyPsychiatric services (Washington, D.C.)2016
Predictors of Poor Response to Depression Treatment in Primary Care.
Observational study in Psychiatric services (Washington, D.C.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Interventions to Foster Mental Health and Reintegration in Individuals Who Are Unemployed: Systematic Review.JMIR public health and surveillance · 2025Pooled it
- Development of a baseline battery to optimize depression treatment assignment in primary care: Balancing breadth and brevity.Journal of affective disorders · 2026Article
- Longitudinal trajectories of symptom change during antidepressant treatment among managed care patients with depression and anxiety.Npj mental health research · 2024Article
- Action recommendations review in community-based therapy and depression and anxiety outcomes: a machine learning approach.BMC psychiatry · 2024Review
- Using Machine Learning to Predict Antidepressant Treatment Outcome From Electronic Health Records.Psychiatric research and clinical practice · 2023Article
- Conceptual Framework of a Psychotherapeutic Consultation in the Workplace: A Qualitative Study.International journal of environmental research and public health · 2022Article
- Concordance of the treatment patterns for major depressive disorders between the Canadian Network for Mood and Anxiety Treatments (CANMAT) algorithm and real-world practice in China.Frontiers in pharmacology · 2022Article
- How well do clinical and demographic characteristics predict Patient Health Questionnaire-9 scores among patients with treatment-resistant major depressive disorder in a real-world setting?Brain and behavior · 2021Article
- Types of Utilization and Types of Treatment Response in a Collaborative Care Approach for Depressive Disorders in Old Age in Primary Care.Frontiers in psychiatry · 2020Article
- Pilot Randomized Trial of a Self-Help Behavioral Activation Mobile App for Utilization in Primary Care.Behavior therapy · 2019Article
- Do Working Conditions of Patients in Psychotherapeutic Consultation in the Workplace Differ from Those in Outpatient Care? Results from an Observational Study.International journal of environmental research and public health · 2018Observational
- Remission in Depression and Associated Factors at Different Assessment Times in Primary Care in Chile.Clinical practice and epidemiology in mental health : CP & EMH · 2018Article
- The effects of patient-centered depression care on patient satisfaction and depression remission.Family practice · 2016Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveDepression is pervasive and costly, and the majority of depression is treated in primary care. The objective of this study was to identify patient characteristics predictive of poor depression outcomes in primary care clinics.
methodsThis observational study followed 792 patients receiving usual care for depression in 83 clinics across Minnesota for at least six months between 2008 and 2010. The primary outcome was an ordinal outcome of remission or response without remission ("response") six months after the start of treatment. The outcome was assessed via telephone administration of the Patient Health Questionnaire-9. Associations of patient characteristics with the primary outcome were assessed by using ordinal logistic regression.
resultsThe majority of patients were female, Caucasian, and employed, and most had some college education and good, very good, or excellent self-rated health. At baseline, 32% had mild depression, 40% moderate depression, 20% moderately severe depression, and 8% severe depression. One-third of patients had psychotherapy or psychiatric care in addition to antidepressant medications. At six months, only 47% of patients obtained depression remission or response. Patients were significantly less likely to experience remission or response if they rated their health as poor or fair or if they were unemployed and were more likely to achieve remission or response if they were younger or had mild depression.
conclusionsPatients with poor or fair health or who were unemployed were less likely to respond to usual depression care and may be good candidates for limited, but potentially more effective, intensive treatment resources for depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.