ReviewHealthcare (Basel, Switzerland)2015
Does Whole Grain Consumption Alter Gut Microbiota and Satiety?
Review in Healthcare (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01403857 (Evaluating Liking, Acceptability and Health Benefits of Grain Products), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating Liking, Acceptability and Health Benefits of Grain Products
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Cereal Fibers and Satiety: A Systematic Review.Nutrition reviews · 2026Pooled it
- Trial
- The Effects of Moderate Whole Grain Consumption on Fasting Glucose and Lipids, Gastrointestinal Symptoms, and Microbiota.Nutrients · 2017Trial
- Diet-microbiome associations in 10,068 individuals from the Human Phenotype Project to guide personalized nutrition.Nature medicine · 2026Article
- Nutritional Habits in Crohn's Disease Onset and Management.Nutrients · 2025Review
- Review
- Impact of fundamental components of the Mediterranean diet on the microbiota composition in blood pressure regulation.Journal of translational medicine · 2024Review
- Food System Transformation and Gut Microbiota Transition: Evidence on Advancing Obesity, Cardiovascular Diseases, and Cancers-A Narrative Review.Foods (Basel, Switzerland) · 2023Review
- Nutritional quality of snacks and beverages sold through vending machines in a large Hispanic-serving urban college campus in the United States: A cross-sectional study.Journal of public health research · 2023Article
- Breakfast consumption trends among young Australian children aged up to 5 years: results from InFANT program.Frontiers in endocrinology · 2023Article
- Insights into the constellating drivers of satiety impacting dietary patterns and lifestyle.Frontiers in nutrition · 2022Review
- Prospective Study of Different Staple Diets of Diabetic Indian Population.Annals of neurosciences · 2021Article
- Comparative Effect of 22 Dietary Sources of Fiber on Gut Microbiota of Healthy HumansFrontiers in nutrition · 2021Article
- Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Review
- Microbiota and metabolic diseases.Endocrine · 2018Review
- Article
- Whole Grains in Amelioration of Metabolic Derangements.Journal of nutritional health & food science · 2016Article
- Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.Cancer metastasis reviews · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes recent studies examining whole grain consumption and its effect on gut microbiota and satiety in healthy humans. Studies comparing whole grains to their refined grain counterparts were considered, as were studies comparing different grain types. Possible mechanisms linking microbial metabolism and satiety are described. Clinical trials show that whole grain wheat, maize, and barley alter the human gut microbiota, but these findings are based on a few studies that do not include satiety components, so no functional claims between microbiota and satiety can be made. Ten satiety trials were evaluated and provide evidence that whole oats, barley, and rye can increase satiety, whereas the evidence for whole wheat and maize is not compelling. There are many gaps in the literature; no one clinical trial has examined the effects of whole grains on satiety and gut microbiota together. Once understanding the impact of whole grains on satiety and microbiota is more developed, then particular grains might be used for better appetite control. With this information at hand, healthcare professionals could make individual dietary recommendations that promote satiety and contribute to weight control.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.