Evidence map›Paper›PMID 27417729›Full record

ArticleDoklady. Biochemistry and biophysics2016

Involvement of transcription factor Oct-1 in the regulation of JAK-STAT signaling pathway in cells of Burkitt lymphoma.

E V Pankratova, A G Stepchenko, I D Krylova, T N Portseva, S G Georgieva

Abstract read
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In one paragraph

Article in Doklady. Biochemistry and biophysics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

E V PankratovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia. tanjnij86@mail.ru.
A G StepchenkoEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia.
I D KrylovaMoscow State Pedagogical University, ul. Malaya Pirogovskaya 1, Moscow, 119992, Russia.
T N PortsevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia.
S G GeorgievaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia.
Engelhardt Institute of Molecular Biology · RUMoscow State Pedagogical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the role of transcription factor Oct-1 in the regulation of expression of genes of the JAK-STAT signaling pathway in the Namalwa Burkitt's lymphoma cell line. Overexpression of Oct-1 isoforms (Oct-1A, Oct-1L, and Oct-1X) causes a decrease in the activity of four genes involved in the JAK-STAT signaling pathway-IFNAR2, STAT1, STAT2, and STAT4. As a result of our research, it was found that genes STAT2 and STAT4 are direct targets for Oct-1 protein.

Indexed as

Burkitt LymphomaCell Line, TumorGene Expression Regulation, NeoplasticHumansOctamer Transcription FactorsProtein IsoformsReal-Time Polymerase Chain ReactionReceptor, Interferon alpha-betaRNA, MessengerSignal TransductionSTAT1 Transcription FactorSTAT2 Transcription FactorSTAT4 Transcription FactorIFNAR2 protein, humanOctamer Transcription FactorsPOU2F3 protein, humanProtein IsoformsReceptor, Interferon alpha-betaRNA, MessengerSTAT1 protein, humanSTAT1 Transcription FactorSTAT2 protein, humanSTAT2 Transcription FactorSTAT4 protein, humanSTAT4 Transcription Factor

Identifiers

PMID27417729
OpenAlexW2461339220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.