ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2016
18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase.
Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- A radioligand for in vitro autoradiography of CSF1R in post-mortem CNS tissues.EJNMMI research · 2024Article
- The Imageable Genome.Nature communications · 2023Article
- [European journal of nuclear medicine and molecular imaging · 2023Article
- Cytochrome P450-derived eicosanoids in brain: From basic discovery to clinical translation.Advances in pharmacology (San Diego, Calif.) · 2023Article
- Oxidation-Cyclisation of Biphenyl Thioethers to Dibenzothiophenium Salts for UltrarapidInternational journal of molecular sciences · 2022Article
- The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO.Journal of medicinal chemistry · 2021Review
- First-in-human neuroimaging of soluble epoxide hydrolase using [European journal of nuclear medicine and molecular imaging · 2021Article
- Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice.International journal of molecular sciences · 2021Article
- PET imaging of soluble epoxide hydrolase in non-human primate brain with [EJNMMI research · 2020Article
- Imaging inflammation and its resolution in health and disease: current status, clinical needs, challenges, and opportunities.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019Review
- An optimized radiosynthesis of [Journal of labelled compounds & radiopharmaceuticals · 2018Article
- Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation.Scientific reports · 2018Article
- Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry.Molecular psychiatry · 2018Review
- PET imaging of the neurovascular interface in cerebrovascular disease.Nature reviews. Neurology · 2017Review
- Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT.Molecular imagingReview
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Soluble epoxide hydrolase (sEH) is a bifunctional enzyme located within cytosol and peroxisomes that converts epoxides to the corresponding diols and hydrolyzes phosphate monoesters. It serves to inactivate epoxyeicosatrienoic acids (EETs), which are generated in the brain to couple neuronal activity and cerebral blood flow in normal and pathologic states. Altered regulation of sEH was observed previously in various neuropathologic disorders including vascular dementia and stroke. Inhibitors of sEH are pursued as agents to mitigate neuronal damage after stroke. We developed N-(3,3-diphenylpropyl)-6-
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.