Evidence map›Paper›PMID 27417557›Full record

ReviewJournal of nephrology2016

Microalbuminuria in primary hypertension: a guide to optimal patient management?

Francesca Viazzi, Francesca Cappadona, Roberto Pontremoli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Decreased Urinary Levels ofInternational journal of molecular sciences · 2020
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Francesca ViazziUniversità degli Studi di Genova and IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, Genoa, Italy.
Francesca CappadonaUniversità degli Studi di Genova and IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, Genoa, Italy.
Roberto PontremoliUniversità degli Studi di Genova and IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, Genoa, Italy. roberto.pontremoli@unige.it.ORCID http://orcid.org/0000-0003-1238-872X
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate assessment of the global risk profile is considered a prerequisite for the optimal management of hypertensive patients. In particular, the evaluation of subclinical organ damage, namely left ventricular hypertrophy, peripheral atherosclerosis and renal function, plays a key role in optimizing therapeutic targets and strategy in individual patients. Urine albumin excretion is a low-cost, easy-to-use test and a powerful predictor of cardiovascular diseases. The search for albuminuria has, therefore, become routine in the evaluation of hypertensive patients. Moreover, albuminuria has been shown to be associated with early signs of extra-renal organ damage such as left ventricular hypertrophy, and carotid atherosclerosis. Under effective antihypertensive treatment, changes in subclinical organ damage over time, especially regression of left ventricular hypertrophy, are paralleled by modification of risk status and may serve as intermediate endpoints for treatment. More recently, changes in albuminuria have also been proposed to reflect changes in the risk of cardiovascular events. If this is confirmed by large well-designed studies, microalbuminuria may not simply be regarded as a risk predictor but become itself an independent target for treatment.

Indexed as

AlbuminuriaAntihypertensive AgentsBlood PressureHumansHypertensionKidneyPrevalenceRemission InductionRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeAntihypertensive AgentsAlbuminuriaCardiovascular riskHypertensionOrgan damageRisk factor

Identifiers

PMID27417557
OpenAlexW2468813696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.