Evidence map›Paper›PMID 27417502›Full record

Trial reportHealth education & behavior : the official publication of the Society for Public Health Education2017

Mediators and Moderators of Improvements in Medication Adherence.

Rebecca Hofer, Hwajung Choi, Rebecca Mase, Angela Fagerlin, Michael Spencer, Michele Heisler

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Health education & behavior : the official publication of the Society for Public Health Education, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Informed Decision Making for Anticoagulation Therapy for Atrial Fibrillation.Medical decision making : an international journal of the Society for Medical Decision Making · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Literature Review of Type 2 Diabetes Management and Health Literacy.Diabetes spectrum : a publication of the American Diabetes Association · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rebecca Hofer1 University of Michigan, Ann Arbor, MI, USA.
Hwajung Choi1 University of Michigan, Ann Arbor, MI, USA.
Rebecca Mase1 University of Michigan, Ann Arbor, MI, USA.
Angela Fagerlin1 University of Michigan, Ann Arbor, MI, USA.
Michael Spencer1 University of Michigan, Ann Arbor, MI, USA.
Michele Heisler1 University of Michigan, Ann Arbor, MI, USA.

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Community Health Worker Diabetes RCT for LatinosR18DK078558 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SPENCER, MICHAEL S · 2008 to 2012
$2.8M
NIDDK NIH HHS P30 DK092926NIDDK NIH HHS R18 DK078558
6 · The paper itself

Abstract

objectiveIn a randomized controlled trial we compared two models of community health worker-led diabetes medication decision support for low-income Latino and African American adults with diabetes. Most outcomes were improved when community health workers used either an interactive e-Health tool or print materials. This article investigates mediators and moderators of improved medication adherence in these two models.

methodBecause both programs significantly improved satisfaction with medication information, medication knowledge, and decisional conflict, we examined whether improvements in each of these outcomes in turn were associated with improvements in self-reported medication adherence, and if so, whether these improvements were mediated by improvements in diabetes self-efficacy or diabetes distress. Potential moderators of improvement included gender, race/ethnicity, age, education, insulin use, health literacy, and baseline self-efficacy, diabetes distress, and A1c.

resultsA total of 176 participants (94%) completed all assessments. After adjusting for potential confounders, only increased satisfaction with medication information was correlated with improved medication adherence ( p = .024). Improved self-efficacy, but not diabetes distress, was associated with improvements in both satisfaction with medication information and medication adherence. However, the Sobel-Goodman Mediation test did not support improvements in self-efficacy as a mechanism by which improved satisfaction led to better adherence. None of the examined variables achieved statistical significance as moderators.

conclusionsImprovements in satisfaction with medication information but not in medication knowledge or decision conflict were associated with improvements in medication adherence. Interventions that target low-income ethnic and racial minorities may need to focus on increasing participants' satisfaction with information provided on diabetes medications and not just improving their knowledge about medications. Future research should explore in more depth other possible mediators and moderators of improvements in medication adherence in low-income minority populations.

Indexed as

Community Health WorkersHealth Knowledge, Attitudes, PracticeMedication AdherenceBlack or African AmericanDiabetes Mellitus, Type 2FemaleHispanic or LatinoHumansMaleMiddle AgedPovertySelf EfficacyTelemedicinechronic disease managementcommunity health workercomputer-mediated health promotiondiabeteshealth behaviorlay health workerspatient educationrandomized controlled trialself-managementtailored e-healthtailored or targeted interventions

Identifiers

PMID27417502
PMCPMC5237412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.