ArticleChildren (Basel, Switzerland)2014
Will Global Climate Change Alter Fundamental Human Immune Reactivity: Implications for Child Health?
Article in Children (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Considering evolved heat tolerance helps predict the immunological consequences of climate change.Seminars in immunopathology · 2026Review
- Climatic Correlates of Brucellosis Transmission in a Semi-Arid Region of Xinjiang, China, 2015-2025: A Maximum Entropy Modeling Study Within a One Health Framework.Animals : an open access journal from MDPI · 2026Article
- Vaccination in Islamic countries: a narrative review.Public health reviews · 2026Review
- The impact of climate, weather, seasonal transitions, and diurnal rhythms on gut microbiota and immune homeostasis.Antonie van Leeuwenhoek · 2025Review
- Effects of Climate Change on the Immune System: A Narrative Review.Health science reports · 2025Article
- Acute generalized peritonitis in children: A 7-year retrospective study of epidemiological, clinical, and therapeutic profiles in southeastern Morocco and 2-year forecast.Journal of education and health promotion · 2025Article
- High temperatures are associated with decreased immune system performance in a wild primate.Science advances · 2024Article
- The Climate Change Burden on Immune Health: Are Persons Living with HIV More at Risk?AIDS research and human retroviruses · 2024Article
- The Impact of Climate Change on Immunity and Gut Microbiota in the Development of Disease.Diseases (Basel, Switzerland) · 2024Review
- Deciphering the relationship between temperature and immunity.Discovery immunology · 2024Review
- A scoping review on climate change and tuberculosis.International journal of biometeorology · 2021Article
- COVID-19 pandemic: the possible influence of the long-term ignorance about climate change.Environmental science and pollution research international · 2021Article
- Tribute to Professor Anthony J. McMichael.Children (Basel, Switzerland) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human immune system is an interface across which many climate change sensitive exposures can affect health outcomes. Gaining an understanding of the range of potential effects that climate change could have on immune function will be of considerable importance, particularly for child health, but has, as yet, received minimal research attention. We postulate several mechanisms whereby climate change sensitive exposures and conditions will subtly impair aspects of the human immune response, thereby altering the distribution of vulnerability within populations-particularly for children-to infection and disease. Key climate change-sensitive pathways include under-nutrition, psychological stress and exposure to ambient ultraviolet radiation, with effects on susceptibility to infection, allergy and autoimmune diseases. Other climate change sensitive exposures may also be important and interact, either additively or synergistically, to alter health risks. Conducting directed research in this area is imperative as the potential public health implications of climate change-induced weakening of the immune system at both individual and population levels are profound. This is particularly relevant for the already vulnerable children of the developing world, who will bear a disproportionate burden of future adverse environmental and geopolitical consequences of climate change.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.