ArticleScientific reports2016
Integration analysis of MKK and MAPK family members highlights potential MAPK signaling modules in cotton.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Mitogen-activated protein kinase (MAPK) gene family identification reveals GhMPK10-mediated regulation of abiotic stress tolerance through protein kinase signaling cascades in cotton.BMC plant biology · 2025Article
- Genome-wide identification and unveiling the role of MAP kinase cascade genes involved in sugarcane response to abiotic stressors.BMC plant biology · 2025Article
- Identification of MAPK Genes inInternational journal of molecular sciences · 2024Article
- Genome-wide identification ofFrontiers in genetics · 2024Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2023Article
- Genome-Wide Characterization of the Mitogen-Activated Protein Kinase Gene Family and Their Expression Patterns in Response to Drought and Colletotrichum Gloeosporioides in Walnut (Plants (Basel, Switzerland) · 2023Article
- Genome-wide identification of MAPK family genes and their response to abiotic stresses in tea plant (Open life sciences · 2022Article
- The Evolution and Expression Profiles ofGenes · 2021Article
- Genome-Wide Identification and Analysis ofInternational journal of molecular sciences · 2021Article
- Dexmedetomidine alleviates LPS‑induced acute lung injury via regulation of the p38/HO‑1 pathway.Molecular medicine reports · 2020Article
- Cloning, molecular and functional characterization by overexpression in Arabidopsis of MAPKK genes from grapevine (Vitis vinifera).BMC plant biology · 2020Article
- Genome-wide identification of MAPK cascade genes reveals the GhMAP3K14-GhMKK11-GhMPK31 pathway is involved in the drought response in cotton.Plant molecular biology · 2020Article
- Identification and Characterization of Mitogen-Activated Protein Kinase (MAPK) Genes in Sunflower (Plants (Basel, Switzerland) · 2019Article
- The cotton MAPK kinase GhMPK20 negatively regulates resistance to Fusarium oxysporum by mediating the MKK4-MPK20-WRKY40 cascade.Molecular plant pathology · 2018Article
- Genome-wide investigation and expression profiling of APX gene family in Gossypium hirsutum provide new insights in redox homeostasis maintenance during different fiber development stages.Molecular genetics and genomics : MGG · 2018Article
- Comparative analysis of plant MKK gene family reveals novel expansion mechanism of the members and sheds new light on functional conservation.BMC genomics · 2018Article
- Identification on mitogen-activated protein kinase signaling cascades by integrating protein interaction with transcriptional profiling analysis in cotton.Scientific reports · 2018Article
- Mitogen-Activated Protein Kinase Cascades in Plant Hormone Signaling.Frontiers in plant science · 2018Review
- Genome-wide characterization of the Rab gene family in Gossypium by comparative analysis.Botanical studies · 2017Article
- Global Identification, Classification, and Expression Analysis of MAPKKK genes: Functional Characterization of MdRaf5 Reveals Evolution and Drought-Responsive Profile in Apple.Scientific reports · 2017Article
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7 authors.
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Abstract
Mitogen-activated protein kinase (MAPK) cascades play a crucial role in plant growth and development, as well as their biotic and abiotic stress responses. As a nodal point of the MAPK cascade, the MKK gene family has not been systematically studied in cotton. Here, we identified 11 putative MKK genes in the Gossypium raimondii genome. Phylogenetic analysis showed that the MKKs were supported by architectures of conserved protein motifs. Expression patterns of MKKs under hormone treatments or abiotic stresses revealed their diverse functions in stress responses. Based on a yeast two hybrid, a total of 63 interactive pairs of MKKs and MAPKs were identified in cotton. Among these, 40 interactive pairs were newly identified compared to that reported previously in Arabidopsis. Integration analysis of the interaction network and expression patterns of MKK and MAPK family members revealed 13 potential MAPK signaling modules that are involved in the complicated cross-talk between hormones and abiotic stresses. Taken together, our data enhance the understanding of the evolution and function of MAPK cascades in cotton, and lay the foundation for the improvement of various defense responses that use MAPK signaling modules in the future.
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