Evidence map›Paper›PMID 27417075›Full record

ArticleBMC health services research2016

Regional differences in recommended cancer treatment for the elderly.

Vivian Ho, Meei-Hsiang Ku-Goto, Hui Zhao, Karen E Hoffman, Benjamin D Smith, Sharon H Giordano

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Clinical epidemiology of the endoscopic, laparoscopic, and surgical resection of malignant gastric tumors in Japan, 2014-2021: a retrospective study using open data from a national claims database.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Observational
  2. Trends in the Cost of Cancer Care: Beyond Drugs.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vivian HoRice University's Baker Institute for Public Policy, Rice University, 6100 Main Street MS-40, Houston, TX, 77005, USA. vho@rice.edu.ORCID 0000-0002-5979-8155
Meei-Hsiang Ku-GotoRice University's Baker Institute for Public Policy, Rice University, 6100 Main Street MS-40, Houston, TX, 77005, USA.
Hui ZhaoThe University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Karen E HoffmanThe University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Benjamin D SmithThe University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Sharon H GiordanoDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1444, Houston, TX, 77030, USA.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USRice University · US

Funding

NATIONAL CANCER PREVENTION AND CONTROL PROGRAMU58DP000824 · DP · TEXAS STATE DEPT OF HEALTH SERVICES · PI DELGADO, EVELYN · 2007 to 2011
$44.3M
NCCDPHP CDC HHS U58 DP000824
6 · The paper itself

Abstract

backgroundLittle is known about regional variation in cancer treatment and its determinants. We compare rates of adherence to treatment guidelines for elderly patients across Texas and whether local specialist supply is an important determinant of treatment variation.

methodsPrevious literature reviewed indicated 7 recommended courses of treatment for colorectal, pancreatic, and prostate cancer. We analyzed Texas Cancer Registry data linked with Medicare claims for the years 2004 to 2007 to study patients with these cancers. We tested for unadjusted and adjusted differences in treatment rates across 22 hospital referral regions (HRR). We tested whether variation in the local supply of specialists treating each cancer was an important determinant of treatment.

resultsWe found significant differences in adjusted treatment rates across regions. For removal and examination of 12+ lymph nodes with colon cancer resection, 13 of 22 HRRs had rates significantly different from the median region. For adjuvant chemotherapy for regional colon cancer, five HRRs significantly differed from the median. For prostate cancer treatment with a favorable diagnosis, nine HRRs differed from the median HRR. Of the 7 treatments, only the local availability of surgeons was an important determinant for excision of lymph nodes for colon cancer patients.

conclusionsThere are significant variations across Texas for seven recommended cancer treatments. No one region has consistently higher or lower treatments than other regions, and local specialist supply is not an important predictor of treatment. Different factors may be determining regional variation in treatment rates across cancer types and treatment options.

Indexed as

GeriatricsAgedChemotherapy, AdjuvantColorectal NeoplasmsFemaleGuideline AdherenceHumansMaleMedicarePancreatic NeoplasmsProstatic NeoplasmsReferral and ConsultationRegistriesTexasUnited StatesColorectal cancerGuidelinesPancreatic resectionProstate cancerSpecialistsTreatment variation

Identifiers

PMID27417075
PMCPMC4946160
OpenAlexW2466950913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.