ArticleDevelopment and psychopathology2017
From alcohol initiation to tolerance to problems: Discordant twin modeling of a developmental process.
Article in Development and psychopathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Behavioral Disinhibition Model of Addiction: A Review and New Findings from the Minnesota Twin Family Study.Behavior genetics · 2026Review
- Does alcohol use and related harm differ based on the age of initiation to alcohol? Results from a prospective cohort study.Addiction (Abingdon, England) · 2026Article
- Early and risky adolescent alcohol use independently predict alcohol, tobacco, cannabis and other drug use in early adulthood in Ireland: a longitudinal analysis of a nationally representative cohort.BMC public health · 2025Article
- Does polygenic risk for substance-related traits predict ages of onset and progression of symptoms?Addiction (Abingdon, England) · 2023Article
- Polygenic risk score for problematic alcohol use predicts heavy drinking and alcohol use disorder symptoms in young adulthood after accounting for adolescent alcohol use and parental alcohol use disorder.Drug and alcohol dependence · 2023Article
- Trajectories of early alcohol use milestones: Interrelations among initiation and progression.Alcoholism, clinical and experimental research · 2021Article
- Punch-Drunk or Drunken Boxing? The Etiology of Alcohol-Related Physical Violence through Adolescence and Young Adulthood.Substance use & misuse · 2021Article
- Comparing the potential causal influence of two indicators of early alcohol use on later alcohol use disorder symptoms.Journal of abnormal psychology · 2020Article
- Developmental considerations in survival models as applied to substance use research.Addictive behaviors · 2019Article
- Faster escalation from first drink to first intoxication as a risk factor for binge and high-intensity drinking among adolescents.Addictive behaviors · 2019Article
- The Importance of Intimate Partner Violence in Within-Relationship and Between-Person Risk for Alcohol-Exposed Pregnancy.Alcoholism, clinical and experimental research · 2019Article
- The Speed of Progression to Tobacco and Alcohol Dependence: A Twin Study.Behavior genetics · 2018Article
- Developmental Etiologies of Alcohol Use and Their Relations to Parent and Peer Influences Over Adolescence and Young Adulthood: A Genetically Informed Approach.Alcoholism, clinical and experimental research · 2017Article
- Grounding alcohol simulation models in empirical and theoretical alcohol research: a model for a Northern Plains population in the United States.System dynamics reviewArticle
Corrections and comments
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Authors and funding
7 authors.
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Abstract
The current study examined a stage-based alcohol use trajectory model to test for potential causal effects of earlier drinking milestones on later drinking milestones in a combined sample of two cohorts of Australian monozygotic and same-sex dizygotic twins (N = 7,398, age M = 30.46, SD = 2.61, 61% male, 56% monozygotic twins). Ages of drinking, drunkenness, regular drinking, tolerance, first nontolerance alcohol use disorder symptom, and alcohol use disorder symptom onsets were assessed retrospectively. Ages of milestone attainment (i.e., age-of-onset) and time between milestones (i.e., time-to-event) were examined via frailty models within a multilevel discordant twin design. For age-of-onset models, earlier ages of onset of antecedent drinking milestones increased hazards for earlier ages of onset for more proximal subsequent drinking milestones. For the time-to-event models, however, earlier ages of onset for the "starting" milestone decreased risk for a shorter time period between the starting and the "ending" milestone. Earlier age of onset of intermediate milestones between starting and ending drinking milestones had the opposite effect, increasing risk for a shorter time period between the starting and ending milestones. These results are consistent with a causal effect of an earlier age of drinking milestone onset on temporally proximal subsequent drinking milestones.
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