Evidence map›Paper›PMID 27416570›Full record

ArticleBlood transfusion = Trasfusione del sangue2016

Italian daily platelet transfusion practice for haematological patients undergoing high dose chemotherapy with or without stem cell transplantation: a survey by the GIMEMA Haemostasis and Thrombosis Working Party.

Giuseppe Tagariello, Giancarlo Castaman, Anna Falanga, Rita Santoro, Mariasanta Napolitano, Sergio Storti, Dino Veneri, Marco Basso, Laura Candiotto, Cristina Tassinari and 3 more

Abstract read
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Article in Blood transfusion = Trasfusione del sangue, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Giuseppe TagarielloTransfusion Service, Haemophilia Centre and Haematology, Castelfranco Veneto Hospital, Castelfranco Veneto, Italy.
Giancarlo CastamanCentre for Bleeding Disorders, Careggi University Hospital, Florence, Italy.
Anna FalangaDepartment of Immunohaematology and Transfusion Medicine and Haemostasis and Thrombosis Centre, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Rita SantoroHaemophilia Centre, Haemostasis and Thrombosis Unit, "Pugliese-Ciaccio" Hospital, Catanzaro, Italy.
Mariasanta NapolitanoUnit of Haematology and Transplantation, University Hospital of Palermo, Palermo, Italy.
Sergio StortiDepartment of Haematology, Catholic University, Rome, Italy.
Dino VeneriDepartment of Medicine; Department of Medicine; University of Verona; Verona, Italy.
Marco BassoTransfusion Service, Haemophilia Centre and Haematology, Castelfranco Veneto Hospital, Castelfranco Veneto, Italy.
Laura CandiottoTransfusion Service, Haemophilia Centre and Haematology, Castelfranco Veneto Hospital, Castelfranco Veneto, Italy.
Cristina TassinariTransfusion Service, Haemophilia Centre and Haematology, Castelfranco Veneto Hospital, Castelfranco Veneto, Italy.
Augusto B FedericiHaematology and Transfusion Medicine, "L. Sacco" University Hospital, Department of Oncology and Haematology-Oncology, University of Milan, Milan, Italy.
Valerio De StefanoDepartment of Haematology, Catholic University, Rome, Italy.
GIMEMA Haemostasis and Thrombosis working party

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFollowing high-dose chemotherapy/bone marrow transplantation, patients are routinely, prophylactically transfused with platelet concentrates (PC) if they have a platelet count ≤10×10 MATERIALS AND

methodsThe GIMEMA Haemostasis and Thrombosis Working Party sent a questionnaire to Italian haematology departments to survey several aspects of daily platelet transfusion practice, such as the cut-off platelet count for transfusion, the evaluation of refractoriness and the type of PC administered.

resultsThe questionnaire was answered by 18 out of 31 centres (58%). A total of 23,162 PC were transfused in 2,396 patients in 2013. The vast majority of centres (95%) transfused PC according to Italian and international guidelines; only a few transfused always at platelet counts ≤20×10 DISCUSSION: Although most Italian haematology departments transfuse PC according to Italian and international guidelines, our survey shows that in routine daily practice physicians do not comply closely with the WHO recommendations on platelet transfusions and monitoring platelet refractoriness. This causes excessive platelet transfusions, with a resulting increase of costs and waste of public health resources.

Identifiers

PMID27416570
PMCPMC5111376

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