ArticlePsychiatry research2016
Negative affect predicts social functioning across schizophrenia and bipolar disorder: Findings from an integrated data analysis.
Article in Psychiatry research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Emotion in Psychosis Onset and Symptom Persistence: A Systematic Review.Early intervention in psychiatry · 2025Pooled it
- Social Functioning Interventions in Psychosis: A Systematic Review.Clinical psychology & psychotherapyPooled it
- Cognitive Mechanisms of Aberrant Self-Referential Social Perception in Psychosis and Bipolar Disorder: Insights From Computational Modeling.Schizophrenia bulletin · 2026Article
- Physical Punishment in Childhood and Adolescence: Related Factors and Outcomes.Journal of child & adolescent trauma · 2025Article
- Response Monitoring Theta-Band Activities Across Emotional Contexts in Schizophrenia and Bipolar Spectrum Disorders.Biological psychiatry global open science · 2025Article
- Stress sensitivity, negative affect, and functioning in an early psychosis clinic.Schizophrenia research · 2025Article
- A Latent Profile Analysis of Psychosis Symptoms to Examine Distress and Depression as Pathways to Suicide Ideation Among Individuals in an Early Phase of Psychosis Illness.Early intervention in psychiatry · 2025Article
- Using the grip strength effort task to measure reward processing dysfunction in schizophrenia and major depressive disorder.Neuroscience applied · 2025Article
- The effect of chronotype on social functioning in schizophrenic patients: examining the chain-mediating role of sleep quality and anxiety.Frontiers in psychiatry · 2025Article
- Global reward processing deficits predict negative symptoms transdiagnostically and transphasically in a severe mental illness-spectrum sample.European archives of psychiatry and clinical neuroscience · 2024Article
- Moment-to-moment affective dynamics in schizophrenia and bipolar disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- Predictive models for social functioning in healthy young adults: A machine learning study integrating neuroanatomical, cognitive, and behavioral data.Social neuroscience · 2022Article
- Affective lability and social functioning in severe mental disorders.European archives of psychiatry and clinical neuroscience · 2022Article
- Affect and Cognitive Closure in Students-A Step to Personalised Education of Clinical Assessment in Psychology with the Use of Simulated and Virtual Patients.Healthcare (Basel, Switzerland) · 2022Article
- Quality versus quantity: Determining real-world social functioning deficits in schizophrenia.Psychiatry research · 2021Article
- Social functioning in schizotypy: How affect influences social behavior in daily life.Journal of clinical psychology · 2020Article
- Habits and Attitudes of Video Gaming and Information Technology Use in People with Schizophrenia: Cross-Sectional Survey.Journal of medical Internet research · 2020Article
- Optimizing Behavioral Paradigms to Facilitate Development of New Treatments for Anhedonia and Reward Processing Deficits in Schizophrenia and Major Depressive Disorder: Study Protocol.Frontiers in psychiatry · 2020Article
- The Fragile Brain: Stress Vulnerability, Negative Affect and GABAergic Neurocircuits in Psychosis.Schizophrenia bulletin · 2019Review
- The Validity of Daily Self-Assessed Perceived Stress Measured Using Smartphones in Healthy Individuals: Cohort Study.JMIR mHealth and uHealth · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, as a predictor of social functioning across serious mental illnesses. One hundred twenty-seven participants with schizophrenia, 113 with schizoaffective disorder, 22 with psychosis not otherwise specified, 58 with bipolar disorder, and 84 healthy controls (N=404) completed self-report negative affect measures. Elevated levels of negative affect were observed in clinical participants compared with healthy controls. For both clinical and healthy control participants, negative affect measures were significantly correlated with social functioning, and consistently explained significant amounts of variance in functioning. For clinical participants, this relationship persisted even after accounting for cognition and positive/negative symptoms. The findings suggest that negative affect is a strong predictor of outcome across these populations and treatment of serious mental illnesses should target elevated negative affect in addition to cognition and positive/negative symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.