ArticleTranslational lung cancer research2016
Primitive neuroectodermal tumor of lungs in adults: a rare series of three cases treated with upfront chemo-radiation.
Article in Translational lung cancer research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Primary Ewing Sarcoma of the Lung: Integrative Analysis of Clinical, Histopathological, Immunohistochemical, and Cytogenetic Features with Literature Review.Indian journal of surgical oncology · 2026Article
- Radioimaging Presentation of a Primitive Neuroectodermal Tumor of the Lung in a 13-Year-Old Female: A Case Report.Cureus · 2024Article
- Successful Radical Pneumonectomy for a Primitive Neuroendodermal Tumor in the Lung: A Case Report and Review of the Literature.Frontiers in surgery · 2021Article
- Expecting the unexpected - Primary mediastinal large B cell lymphoma presenting as huge lung parenchymal mass.Respiratory medicine case reports · 2021Article
- Outcome of multidisciplinary treatment of peripheral primitive neuroectodermal tumor.Scientific reports · 2020Article
- Pazopanib Confers a Progression-free Survival in a Patient with Ewing's Sarcoma/Primitive Neuroectodermal Tumor of the Lung.Internal medicine (Tokyo, Japan) · 2019Article
- Triple-phaseMolecular and clinical oncology · 2017Article
- Pathologic characteristics of primary primitive neuroectodermal tumor in the cervix: a small round cell malignant tumor with glial and epithelial differentiation after neoadjuvant chemotherapy.International journal of clinical and experimental pathology · 2017Article
- Ewing Sarcoma With Emphasis on Extra-skeletal Ewing Sarcoma: A Decade's Experience From a Single Centre in India.Clinical pathology (Thousand Oaks, Ventura County, Calif.)Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primitive neuroectodermal tumors (PNETs) are highly malignant small round blue cell tumors of neuroectodermal origin belonging to either central nervous system, autonomic nervous system or peripheral Askin's or Ewing's group of neoplasms. The latter generally arise in soft tissues of trunk or axial skeleton in children and early adolescents. However in adults this entity is very uncommon. Of all peripheral entities, primary PNET of lungs without chest wall or pleural involvement in adults are extremely rare and have been scarcely reported in world literature as single case reports. We hereby report a series of three interesting cases of adult PNET of lung diagnosed and treated in our institute. The chief presenting complaints of these patients were of chest pain, cough and dyspnea. The cases were diagnosed on the basis of imaging and biopsy which confirmed these lesions to be of PNET histology, confirmed by immunopositivity for neuron specific enolase (NSE), synaptophysin, chromogranin, CD 99 and vimentin on immunohistochemistry (IHC). All three were deemed unresectable in view of infiltration of nearby vital organs and high chances of morbidity. They were treated with upfront chemotherapy followed by conformal radiotherapy (RT) to the residual disease to which they showed significant response both clinically and radiologically. Presently these patients are on regular follow-up for over 6 months without any evidence of progression of disease or distant metastasis.
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