ArticleIDCases2016
Fatal leptospirosis and chikungunya co-infection: Do not forget leptospirosis during chikungunya outbreaks.
Article in IDCases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- A systematic review of human and animal leptospirosis in the Pacific Islands reveals pathogen and reservoir diversity.PLoS neglected tropical diseases · 2018Pooled it
- Leptospirosis in the Caribbean Region between 2000 and 2022: A scoping review of morbidity and mortality.PLoS neglected tropical diseases · 2026Article
- Dengue diagnosis and impact on clinical management: A literature review.PLoS neglected tropical diseases · 2025Review
- Fatal acute undifferentiated febrile illness among clinically suspected leptospirosis cases in Colombia, 2016-2019.PLoS neglected tropical diseases · 2023Article
- Role of Diagnostics in Epidemiology, Management, Surveillance, and Control of Leptospirosis.Pathogens (Basel, Switzerland) · 2022Review
- Assessment of the Current Surveillance System for Human Leptospirosis in Ecuador by Decision Analytic Modeling.Frontiers in public health · 2022Article
- The diagnosis of leptospirosis complicated by pulmonary tuberculosis complemented by metagenomic next-generation sequencing: A case report.Frontiers in cellular and infection microbiology · 2022Article
- Leptospirosis and Coinfection: Should We Be Concerned?International journal of environmental research and public health · 2021Review
- Leptospirosis in French Polynesia: 11 years of surveillance data, 2007-2017.New microbes and new infections · 2019Article
- Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas.Tropical medicine and infectious disease · 2018Article
- Pneumonia in the tropics.Respirology (Carlton, Vic.) · 2018Review
- FatalThe American journal of tropical medicine and hygiene · 2017Article
- Leptospira diversity in animals and humans in Tahiti, French Polynesia.PLoS neglected tropical diseases · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In endemic areas, leptospirosis can be missed by erroneous clinical or laboratory diagnosis of arboviroses or co-infections with arboviruses and an increase in mortality due to leptospirosis has already been reported during arboviruses outbreaks. During the French Polynesian chikungunya virus outbreak in 2014-2015, two leptospirosis and chikungunya co-infections were reported, one of which was fatal. Diagnosis of leptospiroses was delayed in the context of chikungunya outbreak. In the context of arbovirus outbreak, the risk of misdiagnosis of leptospirosis is maximum and clinicians should initiate early antibiotic therapy if leptospirosis is suspected. A delayed diagnosis of leptospirosis can be responsible for fatal outcome. Leptospirosis should be considered even if dengue or chikungunya virus infections are confirmed by reference molecular testing.
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Registered trials
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