Evidence map›Paper›PMID 27413682›Full record

ArticlePreventive medicine reports2016

Comparison of serum lipid management between elderly and non-elderly patients with and without coronary heart disease (CHD).

Rumiko Shimizu, Haruki Torii, Daisuke Yasuda, Yoshinori Hiraoka, Yutaka Furukawa, Akihiro Yoshimoto, Toshio Iwakura, Naoki Matsuoka, Keisuke Tomii, Nobuo Kohara and 2 more

Abstract read
In one paragraph

Article in Preventive medicine reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A comprehensive review of m6 A methylation in coronary heart disease.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rumiko ShimizuDivision of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
Haruki ToriiDivision of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
Daisuke YasudaDivision of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
Yoshinori HiraokaDivision of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
Yutaka FurukawaDepartment of Cardiology, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Akihiro YoshimotoDepartment of Nephrology, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Toshio IwakuraDepartment of Diabetes and Endocrinology, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Naoki MatsuokaDepartment of Diabetes and Endocrinology, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Keisuke TomiiDepartment of Respiratory Medicine, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Nobuo KoharaDepartment of Neurology, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Tohru HashidaDepartment of Pharmacy, Kobe City Medical Center General Hospital, 2-2-1 Minatojimaminami-machi, Chuo-ku, Kobe 650-0047, Japan.
Noriaki KumeDivision of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum lipid management in patients aged ≥ 75 has not been precisely explored. We, therefore, compared the serum lipid management between the two age groups with and without coronary heart disease (CHD). We, therefore, retrospectively reviewed medical charts of patients who were hospitalized in the departments of internal medicine during a period of 14 months. Serum lipid goal attainment was explored by applying the lipid goals for patients aged < 75 to those aged ≥ 75. In 1988 enrolled patients, 717 subjects (36.1%) were aged ≥ 75. Among them, 41.3% and 32.4% of the patients had CHD, 44.2% and 41.0% were primary prevention at high-risk, and 14.5% and 14.6% were primary prevention at moderate-risk in patients aged ≥ 75 and aged < 75, respectively. Serum LDL-C goal achievement rates in CHD were 66.9% and 65.0% in patients aged ≥ 75 and < 75, respectively (p = 0.334). In the primary prevention at high-risk, these rates were 73.5% and 63.3%, in patients aged ≥ 75 and < 75, respectively (p = 0.001). They were 77.9% and 58.1% in primary prevention at moderate-risk aged ≥ 75 and < 75, respectively (p < 0.001). In CHD, lipid-lowering medication subscription rates were significantly lower in patients aged ≥ 75 (60.1%) than those aged < 75 (73.8%, p < 0.001). In conclusion, in CHD, serum lipid goal attainment was comparable between the two age groups although the lipid-lowering drugs were less frequently prescribed in patients aged ≥ 75. Without CHD, it was significantly better in patients aged ≥ 75 than those aged < 75 although the lipid-lowering drug subscription rates were comparable between the two age groups.

Indexed as

Coronary heart disease (CHD)ElderlyLDL-cholesterolLipid-lowering medicationNon-HDL-cholesterol

Identifiers

PMID27413682
PMCPMC4929129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.