ArticleComputational and mathematical methods in medicine2016
A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model.
Article in Computational and mathematical methods in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 46 citations in OpenAlex.
- Article
- Effect of stomach motility on food hydrolysis and gastric emptying: Insight from computational models.Physics of fluids (Woodbury, N.Y. : 1994) · 2022Article
- Computational modeling of drug dissolution in the human stomach: Effects of posture and gastroparesis on drug bioavailability.Physics of fluids (Woodbury, N.Y. : 1994) · 2022Article
- Computational Modeling of Drug Dissolution in the Human Stomach.Frontiers in physiology · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A group of authors has developed a multilevel mathematical model that focuses on functional disorders in a human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up with structure, basic definitions and concepts of a mathematical model at the "macrolevel" that allow describing processes in a human body as a whole. Currently we are working at the "mesolevel" of organs and systems. Due to complexity of the tasks, this paper deals with only one meso-fragment of a digestive system model. It describes some aspects related to modeling multiphase flow in the antroduodenal portion of the gastrointestinal tract. Biochemical reactions, dissolution of food particles, and motor, secretory, and absorbing functions of the tract are taken into consideration. The paper outlines some results concerning influence of secretory function disorders on food dissolution rate and tract contents acidity. The effect which food density has on inflow of food masses from a stomach to a bowel is analyzed. We assume that the future development of the model will include digestive enzymes and related reactions of lipolysis, proteolysis, and carbohydrates breakdown.
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Registered trials
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