ReviewClinical microbiology reviews2016
Diagnosis of Ebola Virus Disease: Past, Present, and Future.
Review in Clinical microbiology reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05067166 (Open-Label, Expanded Access Protocol of a Human Monoclonal Antibody, Ansuvimab), which is not on this map. Cited by 88 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Open-Label, Expanded Access Protocol of a Human Monoclonal Antibody, Ansuvimab (mAb114), Administered As a Therapeutic to Ebola-Infected Patients or As a High-Risk Ebola Post-Exposure Prophylaxis
Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Rapid diagnosis of COVID-19 in the first year of the pandemic: A systematic review.International immunopharmacology · 2021Pooled it
- Mpox in Africa: one year continental response outcomes and way forward.BMJ global health · 2026Article
- The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities.Infectious medicine · 2026Review
- Advances in detecting category A biothreat agents: Toward symptom-driven sensing strategies.Synthetic and systems biotechnology · 2026Review
- On the 50th year responding to Ebola: mapping diagnostic, vaccine, and therapeutic gaps across ebolavirus species.MedScience · 2026Review
- Ebola virus disease: A persistent challenge in global health security.Open veterinary journal · 2026Review
- The geography of waiting: surveillance latency as the hidden driver of Ebola risk in East Africa.Frontiers in public health · 2026Article
- Risk behaviour associated with contracting the Ebola virus at funerals: a study of Liberians attending the funerals of individuals deceased from Ebola.Frontiers in public health · 2026Article
- The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security.Infection and drug resistance · 2026Review
- Specific and visual detection of EBOV based on a one-pot RT-RAA-CRISPR/Cas12a assay.Virologica Sinica · 2025Article
- Evaluating the impact of trade-offs in diagnostic test accuracy, time-to-isolation, and accessibility on outbreak response for the Ebola virus: a mathematical modeling study.BMC infectious diseases · 2025Article
- Rapid laboratory confirmation of the 2025 Sudan Virus Disease (Svd) index case in Uganda.BMC infectious diseases · 2025Article
- Plasmonic Nanoceria: A Plasmon-Enhanced Nanohybrid for Rapid and Sensitive Detection of Ebola Glycoprotein.ACS applied nano materials · 2025Article
- Dengue: epidemiology, diagnosis methods, treatment options, and prevention strategies.Archives of virology · 2025Review
- National burden of Ebola virus disease in Democratic Republic of the Congo: the urgency to act.Annals of medicine and surgery (2012) · 2024Review
- NASBA Coupled to Paper Microfluidics for RNA Detection.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- RNA Analysis Using Immunoassay Detection Format.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Tracing down the updates on Ebola virus surges: An update on anti-ebola therapeutic strategies.Journal of translational internal medicine · 2023Article
- [Confirmatory Diagnosis of Re-Emerging Filoviruses].Jugan geon-gang gwa jilbyeong · 2023Review
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts; however, establishing safe and expeditious testing strategies for this high-biosafety-level pathogen in resource-poor environments remains extremely challenging. Since the discovery of Ebola virus in 1976 via traditional viral culture techniques and electron microscopy, diagnostic methodologies have trended toward faster, more accurate molecular assays. Importantly, technological advances have been paired with increasing efforts to support decentralized diagnostic testing capacity that can be deployed at or near the point of patient care. The unprecedented scope of the 2014-2015 West Africa Ebola epidemic spurred tremendous innovation in this arena, and a variety of new diagnostic platforms that have the potential both to immediately improve ongoing surveillance efforts in West Africa and to transform future outbreak responses have reached the field. In this review, we describe the evolution of Ebola virus disease diagnostic testing and efforts to deploy field diagnostic laboratories in prior outbreaks. We then explore the diagnostic challenges pervading the 2014-2015 epidemic and provide a comprehensive examination of novel diagnostic tests that are likely to address some of these challenges moving forward.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.