Evidence map›Paper›PMID 27413083›Full record

Observational studyGlobal health, science and practice2016

Safety, Acceptability, and Feasibility of Early Infant Male Circumcision Conducted by Nurse-Midwives Using the AccuCirc Device: Results of a Field Study in Zimbabwe.

Webster Mavhu, Natasha Larke, Karin Hatzold, Getrude Ncube, Helen A Weiss, Collin Mangenah, Prosper Chonzi, Owen Mugurungi, Juliet Mufuka, Christopher A Samkange and 3 more

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Global health, science and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Webster MavhuCentre for Sexual Health and HIV/AIDS Research (CeSHHAR), Harare, Zimbabwe University College London, London, United Kingdom.
Natasha LarkeLondon School of Hygiene & Tropical Medicine, London, United Kingdom.
Karin HatzoldPopulation Services International, Harare, Zimbabwe khatzold@psi-zim.co.zw.
Getrude NcubeMinistry of Health and Child Care, Harare, Zimbabwe.
Helen A WeissLondon School of Hygiene & Tropical Medicine, London, United Kingdom.
Collin MangenahCentre for Sexual Health and HIV/AIDS Research (CeSHHAR), Harare, Zimbabwe.
Prosper ChonziHarare City Health, Harare, Zimbabwe.
Owen MugurungiMinistry of Health and Child Care, Harare, Zimbabwe.
Juliet MufukaCentre for Sexual Health and HIV/AIDS Research (CeSHHAR), Harare, Zimbabwe.
Christopher A SamkangeUniversity of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Gerald GwinjiMinistry of Health and Child Care, Harare, Zimbabwe.
Frances M CowanCentre for Sexual Health and HIV/AIDS Research (CeSHHAR), Harare, Zimbabwe University College London, London, United Kingdom.
Ismail TicklayUniversity of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Centre for Sexual Health and HIV AIDS Research · ZWMinistry of Health and Child Welfare · ZWLondon School of Hygiene & Tropical Medicine · GBUniversity of Zimbabwe · ZWUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor prevention of HIV, early infant male circumcision (EIMC) needs to be scaled up in countries with high HIV prevalence. Routine EIMC will maintain the HIV prevention gains anticipated from current adult male circumcision initiatives. We present here the results of a field study of EIMC conducted in Zimbabwe.

methodsThe study was observational and based on the World Health Organization (WHO) framework for clinical evaluation of male circumcision devices. We recruited parents of newborn male infants between August 2013 and July 2014 from 2 clinics. Nurse-midwives used the AccuCirc device to circumcise eligible infants. We followed participants for 14 days after EIMC. Outcome measures were EIMC safety, acceptability, and feasibility.

resultsWe enrolled 500 male infants in the field study (uptake 11%). The infants were circumcised between 6 and 60 days postpartum. The procedure took a median of 17 minutes (interquartile range of 5 to 18 minutes). Mothers' knowledge of male circumcision was extensive. Of the 498 mothers who completed the study questionnaire, 91% knew that male circumcision decreases the risk of HIV acquisition, and 83% correctly stated that this prevention is partial. Asked about their community's perception of EIMC, 40% felt that EIMC will likely be viewed positively in their community; 13% said negatively; and 47% said the perception could be both ways. We observed 7 moderate or severe adverse events (1.4%; 95% confidence interval, 0.4% to 2.4%). All resolved without lasting effects. Nearly all mothers (99%) reported great satisfaction with the outcome, would recommend EIMC to other parents, and would circumcise their next sons.

conclusionThis first field study in sub-Saharan Africa of the AccuCirc device for EIMC demonstrated that EIMC conducted by nurse-midwives with this device is safe, feasible, and acceptable to parents.

Indexed as

Nurse MidwivesAdultCircumcision, MaleFeasibility StudiesFemaleHumansInfantInfant, NewbornMalePatient Acceptance of Health CarePatient SafetyYoung AdultZimbabwe

Identifiers

PMID27413083
PMCPMC4944579
OpenAlexW2467670318

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.