Evidence map›Paper›PMID 27412866›Full record

ArticleHuman brain mapping2016

Neuropsychiatric subsyndromes and brain metabolic network dysfunctions in early onset Alzheimer's disease.

Tommaso Ballarini, Leonardo Iaccarino, Giuseppe Magnani, Nagehan Ayakta, Bruce L Miller, William J Jagust, Maria Luisa Gorno-Tempini, Gil D Rabinovici, Daniela Perani

Open access · greenAbstract read
In one paragraph

Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Observational
  17. Understanding Alzheimer's disease as a disorder of consciousness.Alzheimer's & dementia (New York, N. Y.) · 2021
    Article
  18. Article
  19. Article
  20. Changes in brain glucose metabolism and connectivity in somatoform disorders: anEuropean archives of psychiatry and clinical neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tommaso BallariniUniversità Vita-Salute San Raffaele, Milan, Italy.
Leonardo IaccarinoUniversità Vita-Salute San Raffaele, Milan, Italy.
Giuseppe MagnaniDepartment of Neurology, San Raffaele Hospital, Milan, Italy.
Nagehan AyaktaMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California.
Bruce L MillerMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California.
William J JagustHelen Wills Neuroscience Institute, University of California, Berkeley, California.
Maria Luisa Gorno-TempiniMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California.
Gil D RabinoviciMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California.
Daniela PeraniUniversità Vita-Salute San Raffaele, Milan, Italy.
University Memory and Aging Center · USVita-Salute San Raffaele University · ITUniversity of California, Berkeley · USUniversity of California, San Francisco · US

Funding

PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, YADONG · 2004 to 2018
$27.1M
Progressive Aphasia Cognition Anatomy and ProgressionR01NS050915 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARIA LUISA GORNO TEMPINI · 2004 to 2026
$11.0M
Connectomic imaging in familial and sporadic frontotemporal degenerationU01AG052943 · NIA · UNIVERSITY OF PENNSYLVANIA · PI GORNO TEMPINI, MARIA LUISA, GROSSMAN, MURRAY · 2016 to 2019
$5.9M
Early Age-of-Onset AD: Clinical Heterogeneity and Network DegenerationR01AG045611 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RABINOVICI, GIL DAN · 2014 to 2018
$3.1M
Training program in the neurology of language and neurodegenerative aphasiasK24DC015544 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORNO TEMPINI, MARIA LUISA · 2016 to 2025
$1.9M
NIA NIH HHS P50 AG023501NIA NIH HHS R01 AG045611NIA NIH HHS U01 AG052943NIDCD NIH HHS K24 DC015544NINDS NIH HHS R01 NS050915
6 · The paper itself

Abstract

Neuropsychiatric symptoms (NPSs) often occur in early-age-of-onset Alzheimer's disease (EOAD) and cluster into sub-syndromes (SSy). The aim of this study was to investigate the association between

Indexed as

AffectAge of OnsetAlzheimer DiseaseApathyBrainBrain MappingFemaleFluorodeoxyglucose F18GlucoseHumansMaleMiddle AgedMood DisordersMotor ActivityNeural PathwaysNeuropsychological TestsFluorodeoxyglucose F18GlucoseRadiopharmaceuticalsearly onset Alzheimer's Diseasefrontal lobefunctional networksmetabolic connectivityneuropsychiatric subsyndromespositron-emission tomography

Identifiers

PMID27412866
PMCPMC5521254
OpenAlexW2509196006

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.