Evidence map›Paper›PMID 27412510›Full record

ArticleRadiation protection dosimetry2016

THE DECADE OF THE RABiT (2005-15).

G Garty, H C Turner, A Salerno, A Bertucci, J Zhang, Y Chen, A Dutta, P Sharma, D Bian, M Taveras and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiation protection dosimetry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Development of high-throughput systems for biodosimetry.Radiation protection dosimetry · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Development of electronic training and telescoring tools to increase the surge capacity of dicentric chromosome scorers for radiological/nuclear mass casualty incidents.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2019
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

G GartyCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA gyg2101@cumc.columbia.edu.
H C TurnerCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
A SalernoDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
A BertucciCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
J ZhangDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
Y ChenDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
A DuttaCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
P SharmaCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
D BianDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
M TaverasCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
H WangDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
A BhatlaDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
A BalajeeCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
A W BigelowCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
M RepinCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
O V LyulkoCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.
N SimaanDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
Y L YaoDepartment of Mechanical Engineering, Columbia University, 500 West 120th Street, New York, NY 10027, USA.
D J BrennerCenter for Radiological Research, Columbia University, VC11-230, 630 West 168th Street, New York, NY 10032, USA.

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FORNACE, ALBERT J · 2005 to 2024
$105.4M
High Throughput Technology for Assessing Global DSB Repair CapacityR21ES019494 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRENNER, DAVID JONATHAN · 2011 to 2012
$443k
NIAID NIH HHS U19 AI067773NIEHS NIH HHS R21 ES019494
6 · The paper itself

Abstract

The RABiT (Rapid Automated Biodosimetry Tool) is a dedicated Robotic platform for the automation of cytogenetics-based biodosimetry assays. The RABiT was developed to fulfill the critical requirement for triage following a mass radiological or nuclear event. Starting from well-characterized and accepted assays we developed a custom robotic platform to automate them. We present here a brief historical overview of the RABiT program at Columbia University from its inception in 2005 until the RABiT was dismantled at the end of 2015. The main focus of this paper is to demonstrate how the biological assays drove development of the custom robotic systems and in turn new advances in commercial robotic platforms inspired small modifications in the assays to allow replacing customized robotics with 'off the shelf' systems. Currently, a second-generation, RABiT II, system at Columbia University, consisting of a PerkinElmer cell::explorer, was programmed to perform the RABiT assays and is undergoing testing and optimization studies.

Indexed as

Biological AssayChromosome AberrationsEquipment DesignEquipment Failure AnalysisFlow CytometryHumansPattern Recognition, AutomatedRadiation DosageRadiometryRoboticsSpecimen Handling

Identifiers

PMID27412510
PMCPMC5225976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.