SynthesisImmunologic research2017
Severe manifestations of autoimmune syndrome induced by adjuvants (Shoenfeld's syndrome).
Synthesis in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Review
- Autoimmune syndrome induced by adjuvants (ASIA) following urethral sling placement: A case report.Case reports in women's health · 2026Article
- Article
- Review
- Adjuvant-induced autoimmune syndrome (ASIA syndrome) and the role of sonography in its diagnosis: a case-based review.Rheumatology international · 2025Review
- Symptoms of ASIA Syndrome in a Female Patient with Tattoos - A Case Report.Clinical, cosmetic and investigational dermatology · 2025Article
- The co-occurrence of SAT, hypophysitis, and Schnitzler syndrome after COVID-19 vaccination: the first described case.Hormones (Athens, Greece) · 2024Review
- ASIA Syndrome: State-of-the-Art and Future Perspectives.Vaccines · 2024Review
- Review
- The Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA), Associated with Renal Compromise and Cutaneous Calcinosis: A Case Report and Literature Review.Case reports in nephrology · 2024Article
- When inflammatory stressors dramatically change, disease phenotypes may transform between autoimmune hematopoietic failure and myeloid neoplasms.Frontiers in immunology · 2024Review
- Decision making in breast implant selection for breast reconstruction: A mixed-method study among plastic surgeons.JPRAS open · 2023Article
- Panniculitis as a manifestation of metal-associated autoimmune/inflammatory syndrome induced by adjuvants: a case-based review.Rheumatology international · 2023Review
- Autoimmune/inflammatory syndrome induced by adjuvants (ASIA): past, present, and future implications.Clinical and experimental immunology · 2023Review
- Vaccines and Autoimmunity-From Side Effects to ASIA Syndrome.Medicina (Kaunas, Lithuania) · 2023Review
- Hyaluronic Acid Fillers and ASIA Syndrome: Case Studies.Clinical, cosmetic and investigational dermatology · 2023Article
- Case report of acute encephalitis following the AstraZeneca COVID-19 vaccine.International journal of rheumatic diseases · 2022Article
- Autoimmune post-COVID vaccine syndromes: does the spectrum of autoimmune/inflammatory syndrome expand?Clinical rheumatology · 2022Review
- A Practical Guide to Managing Patients With Systemic Symptoms and Breast Implants.Aesthetic surgery journal · 2022Article
- Dysautonomia Following Tetanus, Diphtheria, and Pertussis Vaccine (Tdap): The First Case of Extreme Cachexia Caused by Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) in a Human.Medicina (Kaunas, Lithuania) · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) encompassing conditions linked to previous exposure to an adjuvant substance. The clinical picture is very heterogeneous, from mild to severe manifestations, including death. However, the systematic analysis of severe ASIA cases has not been performed. The aim of this study was to systematically review the literature on severe ASIA cases. A systematic review of the literature was performed investigating severe ASIA cases. All publications were identified through PubMed, EMBASE, MEDLINE and Cochrane. Articles published from 2011 to 2016 were included. Severe ASIA was arbitrarily defined as follows: major organ involvement, life-threatening conditions, intensive treatment, disability, hospitalization and outcome (survival and death). Cases described before 2011 were excluded. From 2011 to 2016, we identified 4479 ASIA cases, of them 305 fulfilled arbitrary criteria of severe ASIA including our case presentation and 11 deaths. The majority of severe ASIA cases were related to HPV vaccine, silicone, influenza vaccine and mineral oil injections. The interval from exposition to severe manifestation was from 2 days to 23 years. (1) This is the first study that analyzes all cases published on ASIA with severe manifestations. (2) The current HPV vaccine is both effective and generally safe. However, it should be noted that severe autoimmune side effects have been reported in several studies. Severe ASIA may be observed after influenza vaccines, and other vaccines. (3) Efforts should be made to discover the connection between adjuvants, autoimmunity and autoimmune diseases, because there is an increase in cases severe and life-threatening of ASIA.
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Registered trials
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