Evidence map›Paper›PMID 27412286›Full record

ArticleProceedings. Biological sciences2016

Calling in sick: impacts of fever on intra-urban human mobility.

T Alex Perkins, Valerie A Paz-Soldan, Steven T Stoddard, Amy C Morrison, Brett M Forshey, Kanya C Long, Eric S Halsey, Tadeusz J Kochel, John P Elder, Uriel Kitron and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

T Alex PerkinsDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA Department of Entomology and Nematology, University of California, Davis, CA, USA Fogarty International Center, National Institutes of Health, Bethesda, MD, USA taperkins@nd.edu.
Valerie A Paz-SoldanDepartment of Global Health Systems and Development, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.
Steven T StoddardDepartment of Entomology and Nematology, University of California, Davis, CA, USA.
Amy C MorrisonDepartment of Entomology and Nematology, University of California, Davis, CA, USA United States Naval Medical Research Unit No. 6, Lima, Peru.
Brett M ForsheyUnited States Naval Medical Research Unit No. 6, Lima, Peru.
Kanya C LongDepartment of Entomology and Nematology, University of California, Davis, CA, USA Department of Biology, Andrews University, Berrien Springs, MI, USA.
Eric S HalseyUnited States Naval Medical Research Unit No. 6, Lima, Peru.
Tadeusz J KochelUnited States Naval Medical Research Unit No. 6, Lima, Peru.
John P ElderInstitute for Behavioral and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA, USA.
Uriel KitronFogarty International Center, National Institutes of Health, Bethesda, MD, USA Department of Environmental Sciences, Emory University, Atlanta, GA, USA.
Thomas W ScottDepartment of Entomology and Nematology, University of California, Davis, CA, USA Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Gonzalo M Vazquez-ProkopecFogarty International Center, National Institutes of Health, Bethesda, MD, USA Department of Environmental Sciences, Emory University, Atlanta, GA, USA.
Naval Medical Research Unit Six · PEFogarty International Center · USUniversity of California, Davis · USNational Institutes of Health · USSan Diego State University · USTulane University · USUniversity of Notre Dame · US

Funding

Surveillance Core (B)P01AI098670 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORRISON, AMY CELESTE · 2014 to 2018
$7.9M
Measuring Entomological Risk for DengueR01AI069341 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SCOTT, THOMAS WALLACE · 2006 to 2010
$2.3M
NIAID NIH HHS P01 AI098670NIAID NIH HHS R01 AI069341
6 · The paper itself

Abstract

Pathogens inflict a wide variety of disease manifestations on their hosts, yet the impacts of disease on the behaviour of infected hosts are rarely studied empirically and are seldom accounted for in mathematical models of transmission dynamics. We explored the potential impacts of one of the most common disease manifestations, fever, on a key determinant of pathogen transmission, host mobility, in residents of the Amazonian city of Iquitos, Peru. We did so by comparing two groups of febrile individuals (dengue-positive and dengue-negative) with an afebrile control group. A retrospective, semi-structured interview allowed us to quantify multiple aspects of mobility during the two-week period preceding each interview. We fitted nested models of each aspect of mobility to data from interviews and compared models using likelihood ratio tests to determine whether there were statistically distinguishable differences in mobility attributable to fever or its aetiology. Compared with afebrile individuals, febrile study participants spent more time at home, visited fewer locations, and, in some cases, visited locations closer to home and spent less time at certain types of locations. These multifaceted impacts are consistent with the possibility that disease-mediated changes in host mobility generate dynamic and complex changes in host contact network structure.

Indexed as

TravelCase-Control StudiesCitiesDengueFeverHumansLikelihood FunctionsModels, TheoreticalPeruRetrospective Studiesactivity spacecontactdengueinfectionmovementnetwork

Identifiers

PMID27412286
PMCPMC4947886
OpenAlexW2473818554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.