ArticleProceedings. Biological sciences2016
Larval food quantity affects the capacity of adult mosquitoes to transmit human malaria.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 133 citations in OpenAlex.
- Mosquito population dynamics are shaped by interactions among larval density, temperature, and relative humidity.Ecology · 2026Article
- Impact of light pollution spectra and intensity on the development and mortality of tiger mosquito (Aedes albopictus) larvae.The Journal of experimental biology · 2026Article
- Beyond Temperature: Relative Humidity Systematically Shifts Juvenile Thermal Performance and Projected Population Growth in a Malaria Vector.Ecology letters · 2026Article
- Diurnal fluctuating temperature and larval resource level interact to influence the life history and behaviour of disease-transmitting mosquitoes.Parasites & vectors · 2026Article
- Phenotypic variation in populations of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission.PLoS neglected tropical diseases · 2025Article
- Effects of temperature and nutrition stress on Anopheles stephensi, an Indian urban malaria vector.Malaria journal · 2025Article
- Heterogeneous impacts for malaria control from larviciding across villages and considerations for monitoring and evaluation.PLoS pathogens · 2025Article
- Modelling the effects of diurnal temperature variation on malaria infection dynamics in mosquitoes.Communications biology · 2025Article
- Impact of the intensity of infection in birds on Plasmodium development within Culex pipiens mosquitoes.Parasites & vectors · 2025Article
- Contrasting vector competence of three main East African Anopheles malaria vector mosquitoes for Plasmodium falciparum.Scientific reports · 2025Article
- Article
- Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes.Parasites & vectors · 2024Article
- Estimating the effects of temperature on transmission of the human malaria parasite, Plasmodium falciparum.Nature communications · 2024Article
- Development of circulating isolates of Plasmodium falciparum is accelerated in Anopheles vectors with reduced reproductive output.PLoS neglected tropical diseases · 2024Article
- Evolutionary modelling indicates that mosquito metabolism shapes the life-history strategies of Plasmodium parasites.Nature communications · 2023Article
- Larval diet and temperature alter mosquito immunity and development: using body size and developmental traits to track carry-over effects on longevity.Parasites & vectors · 2023Article
- Nutritional stress compromises mosquito fitness and antiviral immunity, while enhancing dengue virus infection susceptibility.Communications biology · 2023Article
- Intervention reducing malaria parasite load in vector mosquitoes: No impact on Plasmodium falciparum extrinsic incubation period and the survival of Anopheles gambiae.PLoS pathogens · 2023Article
- Mosquito bites and stage-specific antibody responses against Plasmodium falciparum in southern Ghana.Malaria journal · 2023Article
- Adipokinetic hormone signaling in the malaria vector Anopheles gambiae facilitates Plasmodium falciparum sporogony.Communications biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Adult traits of holometabolous insects are shaped by conditions experienced during larval development, which might impact interactions between adult insect hosts and parasites. However, the ecology of larval insects that vector disease remains poorly understood. Here, we used Anopheles stephensi mosquitoes and the human malaria parasite Plasmodium falciparum, to investigate whether larval conditions affect the capacity of adult mosquitoes to transmit malaria. We reared larvae in two groups; one group received a standard laboratory rearing diet, whereas the other received a reduced diet. Emerging adult females were then provided an infectious blood meal. We assessed mosquito longevity, parasite development rate and prevalence of infectious mosquitoes over time. Reduced larval food led to increased adult mortality and caused a delay in parasite development and a slowing in the rate at which parasites invaded the mosquito salivary glands, extending the time it took for mosquitoes to become infectious. Together, these effects increased transmission potential of mosquitoes in the high food regime by 260-330%. Such effects have not, to our knowledge, been shown previously for human malaria and highlight the importance of improving knowledge of larval ecology to better understand vector-borne disease transmission dynamics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.