ArticleProceedings. Biological sciences2016
Mutations in different pigmentation genes are associated with parallel melanism in island flycatchers.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 72 citations in OpenAlex.
- Convergent Evolution and the Epigenome.Epigenomes · 2025Review
- Plumage polymorphism in the black sparrowhawk (Accipiter melanoleucus) is strongly associated with the expression level of agouti signaling protein.The Journal of heredity · 2025Article
- Genetic Basis and Evolution of Structural Color Polymorphism in an Australian Songbird.Molecular biology and evolution · 2024Article
- The Genetic Basis of Melanism in Abert's Squirrel (Animals : an open access journal from MDPI · 2024Article
- Photographic documentation of melanism in bobcats (Ecology and evolution · 2024Article
- Selective sweeps on different pigmentation genes mediate convergent evolution of island melanism in two incipient bird species.PLoS genetics · 2022Article
- An enhancer ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Concerted variation in melanogenesis genes underlies emergent patterning of plumage in capuchino seedeaters.Proceedings. Biological sciences · 2022Article
- Variation in Genetic Mechanisms for Plumage Polymorphism in Skuas (Stercorarius).The Journal of heredity · 2021Article
- Extensive hybridization reveals multiple coloration genes underlying a complex plumage phenotype.Proceedings. Biological sciences · 2021Article
- Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The genomics of coloration provides insights into adaptive evolution.Nature reviews. Genetics · 2020Review
- Gene Flow in the Müllerian Mimicry Ring of a Poisonous Papuan Songbird Clade (Pitohui; Aves).Genome biology and evolution · 2019Article
- Multiple origins of melanism in two species of North American tree squirrel (Sciurus).BMC evolutionary biology · 2019Article
- Metabolic physiology explains macroevolutionary trends in the melanic colour system across amniotes.Proceedings. Biological sciences · 2018Article
- Admixture mapping in a hybrid zone reveals loci associated with avian feather coloration.Proceedings. Biological sciences · 2017Article
- A nonrandom subset of olfactory genes is associated with host preference in the fruit flyEvolution letters · 2017Article
- Repeated divergent selection on pigmentation genes in a rapid finch radiation.Science advances · 2017Article
- A novel locus on chromosome 1 underlies the evolution of a melanic plumage polymorphism in a wild songbird.Royal Society open science · 2017Article
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The independent evolution of similar traits across multiple taxa provides some of the most compelling evidence of natural selection. Little is known, however, about the genetic basis of these convergent or parallel traits: are they mediated by identical or different mutations in the same genes, or unique mutations in different genes? Using a combination of candidate gene and reduced representation genomic sequencing approaches, we explore the genetic basis of and the evolutionary processes that mediate similar plumage colour shared by isolated populations of the Monarcha castaneiventris flycatcher of the Solomon Islands. A genome-wide association study (GWAS) that explicitly controlled for population structure revealed that mutations in known pigmentation genes are the best predictors of parallel plumage colour. That is, entirely black or melanic birds from one small island share an amino acid substitution in the melanocortin-1 receptor (MC1R), whereas similarly melanic birds from another small island over 100 km away share an amino acid substitution in a predicted binding site of agouti signalling protein (ASIP). A third larger island, which separates the two melanic populations, is inhabited by birds with chestnut bellies that lack the melanic MC1R and ASIP allelic variants. Formal FST outlier tests corroborated the results of the GWAS and suggested that strong, directional selection drives the near fixation of the MC1R and ASIP variants across islands. Our results, therefore, suggest that selection acting on different mutations with large phenotypic effects can drive the evolution of parallel melanism, despite the relatively small population size on islands.
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