ArticleBMJ open2016
Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations: protocol for the COPE study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Limitations for health research with restricted data collection from UK primary care.Pharmacoepidemiology and drug safety · 2019Pooled it
- Exposure measurement error in air-pollution epidemiology and its determinants: results from the MELONS study.International journal of epidemiology · 2026Article
- Investigating the Consequences of Measurement Error of Gradually More Sophisticated Long-Term Personal Exposure Models in Assessing Health Effects: The London Study (MELONS).Research report (Health Effects Institute) · 2025Article
- A machine learning framework for short-term prediction of chronic obstructive pulmonary disease exacerbations using personal air quality monitors and lifestyle data.Scientific reports · 2025Article
- Air pollution and respiratory health in patients with COPD: should we focus on indoor or outdoor sources?Thorax · 2024Article
- Early detection of COPD patients' symptoms with personal environmental sensors: a remote sensing framework using probabilistic latent component analysis with linear dynamic systems.Neural computing & applications · 2023Article
- Automated classification of time-activity-location patterns for improved estimation of personal exposure to air pollution.Environmental health : a global access science source · 2022Article
- Environmental effects on acute exacerbations of respiratory diseases: A real-world big data study.The Science of the total environment · 2022Article
- Digital Healthcare for Airway Diseases from Personal Environmental Exposure.Yonsei medical journal · 2022Review
- Personal exposure to air pollution and respiratory health of COPD patients in London.The European respiratory journal · 2021Article
- Associations between daily air quality and hospitalisations for acute exacerbation of chronic obstructive pulmonary disease in Beijing, 2013-17: an ecological analysis.The Lancet. Planetary health · 2019Article
- Characterising low-cost sensors in highly portable platforms to quantify personal exposure in diverse environments.Atmospheric measurement techniques · 2019Article
- Personalized medicine for patients with COPD: where are we?International journal of chronic obstructive pulmonary disease · 2019Review
- Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research.NPJ primary care respiratory medicine · 2018Article
- How Sensors Might Help Define the External Exposome.International journal of environmental research and public health · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
introductionRelationships between exacerbations of chronic obstructive pulmonary disease (COPD) and environmental factors such as temperature, humidity and air pollution are not well characterised, due in part to oversimplification in the assignment of exposure estimates to individuals and populations. New developments in miniature environmental sensors mean that patients can now carry a personal air quality monitor for long periods of time as they go about their daily lives. This creates the potential for capturing a direct link between individual activities, environmental exposures and the health of patients with COPD. Direct associations then have the potential to be scaled up to population levels and tested using advanced human exposure models linked to electronic health records. METHODS AND ANALYSIS: This study has 5 stages: (1) development and deployment of personal air monitors; (2) recruitment and monitoring of a cohort of 160 patients with COPD for up to 6 months with recruitment of participants through the Clinical Practice Research Datalink (CPRD); (3) statistical associations between personal exposure with COPD-related health outcomes; (4) validation of a time-activity exposure model and (5) development of a COPD prediction model for London. ETHICS AND DISSEMINATION: The Research Ethics Committee for Camden and Islington has provided ethical approval for the conduct of the study. Approval has also been granted by National Health Service (NHS) Research and Development and the Independent Scientific Advisory Committee. The results of the study will be disseminated through appropriate conference presentations and peer-reviewed journals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.