ArticlePathology oncology research : POR2017
Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer.
Article in Pathology oncology research : POR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Downregulated expression of lncRNA TUBA4B predicts unfavorable prognosis and suppresses glioma progression by sponging miR-183 to regulate SMAD4 expression.Archives of medical science : AMS · 2024Article
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- Heterogeneous microenvironment analysis to explore the potential regulatory role of endothelial-mesenchymal transition in idiopathic pulmonary fibrosis.Annals of translational medicine · 2022Article
- GraphSynergy: a network-inspired deep learning model for anticancer drug combination prediction.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- LINC01619 promotes non-small cell lung cancer development via regulating PAX6 by suppressing microRNA-129-5p.American journal of translational research · 2020Article
- lncRNA‑u50535 promotes the progression of lung cancer by activating CCL20/ERK signaling.Oncology reports · 2019Article
- LncRNA TP73-AS1 interacted with miR-141-3p to promote the proliferation of non-small cell lung cancer.Archives of medical science : AMS · 2019Article
- SFTA1P, LINC00968, GATA6-AS1, TBX5-AS1, and FEZF1-AS1 are crucial long non-coding RNAs associated with the prognosis of lung squamous cell carcinoma.Oncology letters · 2019Article
- Methylation and transcriptome analysis reveal lung adenocarcinoma-specific diagnostic biomarkers.Journal of translational medicine · 2019Article
- Long non‑coding RNA NORAD promotes cell proliferation and glycolysis in non‑small cell lung cancer by acting as a sponge for miR‑136‑5p.Molecular medicine reports · 2019Article
- LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.Cancer cell international · 2019Article
- Knockdown of long non-coding RNA SNHG5 inhibits malignant cellular phenotypes of glioma via Wnt/CTNNB1 signaling pathway.Journal of Cancer · 2019Article
- Linc00483 as ceRNA regulates proliferation and apoptosis through activating MAPKs in gastric cancer.Journal of cellular and molecular medicine · 2018Article
- Downregulation of lncRNA TUBA4B is Associated with Poor Prognosis for Epithelial Ovarian Cancer.Pathology oncology research : POR · 2018Article
- Identification and validation a TGF-β-associated long non-coding RNA of head and neck squamous cell carcinoma by bioinformatics method.Journal of translational medicine · 2018Article
- Silence of Long Noncoding RNA NEAT1 Inhibits Malignant Biological Behaviors and Chemotherapy Resistance in Gastric Cancer.Pathology oncology research : POR · 2018Article
- Long non-coding RNA CRYBG3 regulates glycolysis of lung cancer cells by interacting with lactate dehydrogenase A.Journal of Cancer · 2018Article
- Article
- Long non-coding RNA CDKN2B antisense RNA 1 gene inhibits Gemcitabine sensitivity in bladder urothelial carcinoma.Journal of Cancer · 2018Article
- Overexpression of lncRNA IGFBP4-1 reprograms energy metabolism to promote lung cancer progression.Molecular cancer · 2017Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to unveil the clinical roles and biological function of lncRNA TUBA4B in on-small cell lung cancer (NSCLC). The relative expression level of TUBA4B was estimated by qPCR in 114 pairs of NSCLC and NT samples and the relation of TUBA4B to clinical data of NSCLC patients was analyzed. We found TUBA4B was lower expressed in NSCLC and five cell lines. The lower expression of TUBA4B was remarkably correlated with advanced TNM stage and lymph node metastasis and served as a predictor for overall survival of NSCLC. After overexpression of TUBA4B, cell proliferation ability of A549 and NCI-H1299 remarkably decreased. Our study ascertained low expression TUBA4B in NSCLC tissue, cell lines and is a poor predictor for prognosis and can regulate cell proliferation in NSCLC.
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