Evidence map›Paper›PMID 27411839›Full record

ArticleHeart (British Cardiac Society)2016

Primary percutaneous coronary intervention for ST elevation myocardial infarction in nonagenarians.

Thibaut Petroni, Azfar Zaman, Jean-Louis Georges, Nadjib Hammoudi, Emmanuel Berman, Amit Segev, Jean-Michel Juliard, Olivier Barthelemy, Johanne Silvain, Rémi Choussat and 2 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Heart (British Cardiac Society), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Thibaut PetroniCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Azfar ZamanFreeman Hospital and Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
Jean-Louis GeorgesCentre Hospitalier de Versailles, André Mignot Hospital, Le Chesnay, France.
Nadjib HammoudiCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Emmanuel BermanCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Amit SegevHeart Institute, Chaim Sheba Medical Center, Tel-Hashomer, Israël.
Jean-Michel JuliardBichat Hospital, APHP, Paris, France.
Olivier BarthelemyCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Johanne SilvainCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Rémi ChoussatCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Claude Le FeuvreCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Gérard HelftCardiology Institute, Pitié-Salpêtrière Hospital, UPMC, APHP, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRPitié-Salpêtrière Hospital · FRSorbonne Université · FRCentre Hospitalier de Versailles · FRNewcastle University · GBSheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess outcomes following primary percutaneous coronary intervention (PCI) for ST-segment elevation acute myocardial infarction (STEMI) in nonagenarian patients.

methodsWe conducted a multicentre retrospective study between 2006 and 2013 in five international high-volume centres and included consecutive all-comer nonagenarians treated with primary PCI for STEMI. There were no exclusion criteria. We enrolled 145 patients and collected demographic, clinical and procedural data. Severe clinical events and mortality at 6 months and 1 year were assessed.

resultsCardiogenic shock was present at admission in 21%. Median (IQR) delay between symptom onset and balloon was 3.7 (2.4-5.6) hours and 60% of procedures were performed through the transradial approach. Successful revascularisation of the culprit vessel was obtained in 86% of the cases (thrombolysis in myocardial infarction flow of 2 or 3). Major or clinically relevant bleeding was observed in 4% of patients. Median left ventricular ejection fraction post PCI was 41.5% (32.0-50.0). The in-hospital mortality was 24%, with 6 months and 1-year survival rates of 61% and 53%, respectively.

conclusionsIn our study, primary PCI in nonagenarians with STEMI was achieved and feasible through a transradial approach. It is associated with a high rate of reperfusion of the infarct-related artery and 53% survival at 1 year. These results suggest that primary PCI may be offered in selected nonagenarians with acute myocardial infarction.

Indexed as

Angioplasty, Balloon, CoronaryAged, 80 and overAge FactorsCoronary AngiographyEuropeFeasibility StudiesFemaleHemorrhageHospital MortalityHospitals, High-VolumeHumansIsraelKaplan-Meier EstimateMaleProportional Hazards ModelsPunctures

Identifiers

PMID27411839
PMCPMC5099211
OpenAlexW2470213607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.