Evidence map›Paper›PMID 27411372›Full record

ArticleMicrobiologyOpen2017

Influence of temperature, mixing, and addition of microcystin-LR on microcystin gene expression in Microcystis aeruginosa.

Pia I Scherer, Uta Raeder, Juergen Geist, Katrin Zwirglmaier

Open access · goldAbstract read
In one paragraph

Article in MicrobiologyOpen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Ecotoxicology ofToxins · 2026
    Review
  3. Impact of high temperature and UVR exposure on the microcystin production and mcyB gene expression in the cyanobacterium Microcystis aeruginosa.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  4. How warming impacts the photosynthetic physiology of the bloom-forming cyanobacterium, Microcystis aeruginosa, under UV exposure.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  5. Article
  6. Review
  7. Current research scenario for biological effect of exogenous factors on microcystin synthesis.Environmental science and pollution research international · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pia I SchererAquatic Systems Biology Unit, Limnological Research Station Iffeldorf, Department of Ecology and Ecosystem Management, Technical University of Munich, Munich, Germany.ORCID 0000-0002-3998-8875
Uta RaederAquatic Systems Biology Unit, Limnological Research Station Iffeldorf, Department of Ecology and Ecosystem Management, Technical University of Munich, Munich, Germany.
Juergen GeistAquatic Systems Biology Unit, Limnological Research Station Iffeldorf, Department of Ecology and Ecosystem Management, Technical University of Munich, Munich, Germany.
Katrin ZwirglmaierAquatic Systems Biology Unit, Limnological Research Station Iffeldorf, Department of Ecology and Ecosystem Management, Technical University of Munich, Munich, Germany.
Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanobacteria, such as the toxin producer Microcystis aeruginosa, are predicted to be favored by global warming both directly, through elevated water temperatures, and indirectly, through factors such as prolonged stratification of waterbodies. M. aeruginosa is able to produce the hepatotoxin microcystin, which causes great concern in freshwater management worldwide. However, little is known about the expression of microcystin synthesis genes in response to climate change-related factors. In this study, a new RT-qPCR assay employing four reference genes (GAPDH, gltA, rpoC1, and rpoD) was developed to assess the expression of two target genes (the microcystin synthesis genes mcyB and mcyD). This assay was used to investigate changes in mcyB and mcyD expression in response to selected environmental factors associated with global warming. A 10°C rise in temperature significantly increased mcyB expression, but not mcyD expression. Neither mixing nor the addition of microcystin-LR (10 μg L

Indexed as

ATP-Binding Cassette TransportersBacterial ToxinsClimate ChangeEnvironmentEnvironmental MicrobiologyGene Expression Regulation, BacterialHot TemperatureMarine ToxinsMicrocystinsMicrocystisReal-Time Polymerase Chain ReactionStress, PhysiologicalWater MicrobiologyATP-Binding Cassette TransportersBacterial Toxinscyanoginosin LRMarine ToxinsMcyH protein, Microcystis aeruginosamicrocystinMicrocystinsgene expressionmcyBmcyDMicrocystis aeruginosaqPCRtoxic cyanobacteria

Identifiers

PMID27411372
PMCPMC5300888
OpenAlexW2469728798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.