ArticleBMC neurology2016
Living alone predicts mortality in patients with ischemic stroke before 70 years of age: a long-term prospective follow-up study.
Article in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impact of alcohol consumption on stroke prognosis: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- The impact of social relationships on the risk of stroke and post-stroke mortality: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Rehabilitation Transition Program to Improve Community Participation Among Stroke Survivors: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Community Participation Transition After Stroke (COMPASS) Randomized Controlled Trial: Effect on Adverse Health Events.Archives of physical medicine and rehabilitation · 2024Trial
- Age-, sex-, and stroke type-specific associations of lifestyle factors with 30-day poststroke case-fatality: a nationwide cohort study.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- AI home monitoring for behavioral markers of cerebrovascular disease.NPJ digital medicine · 2026Article
- Predicting post-stroke functional outcome using explainable machine learning and integrated data.Scientific reports · 2026Article
- Association between living arrangements and health outcomes among stroke survivors in China.BMC geriatrics · 2025Article
- Article
- Gender-Specific Population Attributable Fractions for Cardiovascular Disease and All-Cause Mortality Associated with Living Arrangement in Community-Dwelling Older People.Journal of general internal medicine · 2025Article
- Social Determinants of Health Framework Identifies Patients at Risk for Loss to Follow-Up After Stroke.Journal of the American Heart Association · 2025Article
- Marital status and risk of cardiovascular disease - a multi-analyst study in epidemiology.European journal of epidemiology · 2025Article
- Clinical Characteristics and Outcomes of Aneurysmal Subarachnoid Hemorrhage Patients Who Live Alone.Neurologia medico-chirurgica · 2024Observational
- Association between Living Conditions and the Risk Factors, Etiology, and Outcome of Ischemic Stroke in Young Adults.Internal medicine (Tokyo, Japan) · 2023Article
- A retrospective study on return to living alone of stroke patients who were living alone before stroke.Journal of physical therapy science · 2023Article
- Article
- The implementation of a community-centered first aid education program for older adults-community health workers perceived barriers.BMC health services research · 2023Article
- Observational
- Physical inactivity before stroke is associated with dependency in basic activities of daily living 3 months after stroke.Frontiers in neurology · 2023Article
- Social Factors Contributing to Healthcare Service Requirements during the First COVID-19 Lockdown among Older Adults.Healthcare (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLiving alone is associated with increased mortality after myocardial infarction but little data is available about whether this applies to prognosis after stroke. We aimed to examine the association between living situation and long-term mortality in patients with ischemic stroke and a control group, and to explore whether this association is modified by patient gender.
methodsThis is a prospective case-control study of 600 patients with ischemic stroke before 70 years of age and 600 age- and sex-matched controls who have been included in the Sahlgrenska Study on Ischemic Stroke. Mortality data were collected through national registers and medical records. We used Cox regression models for identifying predictors of mortality.
resultsIn the entire sample, mean age was 57 years, proportion of males 64%, proportion living alone 28%, and median follow-up 8.6 years. Mortality rates were 36% among patients living alone, 17% among cohabitant patients, 15% among controls living alone, and 9% among cohabitant controls. Living alone was an independent predictor of all-cause mortality in cases after adjustment for stroke severity, stroke subtype, and vascular risk factors including physical activity, alcohol consumption, and socioeconomic status. A significant interaction was found between gender and living situation; the adjusted hazard ratio for mortality was 3.47 (95% Confidence Interval 2.13-5.65) in male patients living alone, whereas no significant association was observed in women. Living alone was also a predictor of vascular mortality among cases and of all-cause mortality among controls.
conclusionsLiving alone is associated with increased long-term mortality after ischemic stroke in men. Further prospective studies are needed to confirm the observed gender difference and to identify modifiable factors underlying this increased risk.
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