Evidence map›Paper›PMID 27410966›Full record

ArticlePloS one2016

Age Targeting of Voluntary Medical Male Circumcision Programs Using the Decision Makers' Program Planning Toolkit (DMPPT) 2.0.

Katharine Kripke, Marjorie Opuni, Melissa Schnure, Sema Sgaier, Delivette Castor, Jason Reed, Emmanuel Njeuhmeli, John Stover

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
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  3. Trial
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  5. Article
  6. Preventing HIV Among Adolescent Boys and Young Men Through PEPFAR-Supported Voluntary Medical Male Circumcision in 15 Sub-Saharan African Countries, 2018-2021.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
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  11. The development of an explanatory model for voluntary medical male circumcision in KwaZulu-Natal, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2021
    Article
  12. Effectiveness of Voluntary Medical Male Circumcision for Human Immunodeficiency Virus Prevention in Rakai, Uganda.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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  13. Article
  14. Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Katharine KripkeHealth Policy Project, Avenir Health, Washington, DC, United States of America.
Marjorie OpuniUnited Nations Joint Programme on HIV/AIDS (UNAIDS), Geneva, Switzerland.
Melissa SchnureHealth Policy Project, Futures Group, Washington, DC, United States of America.
Sema SgaierBill & Melinda Gates Foundation, Seattle, WA, United States of America.
Delivette CastorOffice of the U.S. Global AIDS Coordinator and Health Diplomacy, Washington, DC, United States of America.
Jason ReedOffice of the U.S. Global AIDS Coordinator and Health Diplomacy, Washington, DC, United States of America.
Emmanuel NjeuhmeliUSAID, Washington, DC, United States of America.ORCID http://orcid.org/0000-0001-5370-4827
John StoverHealth Policy Project, Avenir Health, Glastonbury, CT, United States of America.
Avenir Health · USFutures Group (United States) · USGates Foundation · USJoint United Nations Programme on HIV/AIDS · CHUnited States Agency for International Development · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite considerable efforts to scale up voluntary medical male circumcision (VMMC) for HIV prevention in priority countries over the last five years, implementation has faced important challenges. Seeking to enhance the effect of VMMC programs for greatest and most immediate impact, the U. S. President's Plan for AIDS Relief (PEPFAR) supported the development and application of a model to inform national planning in five countries from 2013-2014. METHODS AND

findingsThe Decision Makers' Program Planning Toolkit (DMPPT) 2.0 is a simple compartmental model designed to analyze the effects of client age and geography on program impact and cost. The DMPPT 2.0 model was applied in Malawi, South Africa, Swaziland, Tanzania, and Uganda to assess the impact and cost of scaling up age-targeted VMMC coverage. The lowest number of VMMCs per HIV infection averted would be produced by circumcising males ages 20-34 in Malawi, South Africa, Tanzania, and Uganda and males ages 15-34 in Swaziland. The most immediate impact on HIV incidence would be generated by circumcising males ages 20-34 in Malawi, South Africa, Tanzania, and Uganda and males ages 20-29 in Swaziland. The greatest reductions in HIV incidence over a 15-year period would be achieved by strategies focused on males ages 10-19 in Uganda, 15-24 in Malawi and South Africa, 10-24 in Tanzania, and 15-29 in Swaziland. In all countries, the lowest cost per HIV infection averted would be achieved by circumcising males ages 15-34, although in Uganda this cost is the same as that attained by circumcising 15- to 49-year-olds.

conclusionsThe efficiency, immediacy of impact, magnitude of impact, and cost-effectiveness of VMMC scale-up are not uniform; there is important variation by age group of the males circumcised and countries should plan accordingly.

Indexed as

Circumcision, MaleNational Health ProgramsVoluntary ProgramsAdolescentAdultAge FactorsChildCost-Benefit AnalysisDecision MakingEswatiniHealth PolicyHIV InfectionsHumansIncidenceMalawiMale

Identifiers

PMID27410966
PMCPMC4943717
OpenAlexW2463738392

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.