Evidence map›Paper›PMID 27410912›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2016

CLINICAL CHARACTERISTICS, OUTCOMES AND RISK FACTORS FOR DEATH AMONG CRITICALLY ILL PATIENTS WITH HIV-RELATED ACUTE KIDNEY INJURY.

Leonardo Duarte Sobreira Luna, Douglas de Sousa Soares, Geraldo Bezerra da Silva Junior, Malena Gadelha Cavalcante, Lara Raissa Cavalcante Malveira, Gdayllon Cavalcante Meneses, Eanes Delgado Barros Pereira, Elizabeth De Francesco Daher

Open access · diamondAbstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Overview of Renal Replacement Therapy Use in a General Intensive Care Unit.International journal of environmental research and public health · 2022
    Observational
  3. Death-related factors in HIV/AIDS patients undergoing hemodialysis in an intensive care unit.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021
    Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Leonardo Duarte Sobreira LunaFederal University of Ceará, School of Medicine, Division of Nephrology, Department of Internal Medicine. Fortaleza, CE, Brazil. E-mails: leonardo.luna@hotmail.com; douglas.sousa.soares@gmail.com; lara.raissa@gmail.com; ef.daher@uol.com.br.
Douglas de Sousa SoaresFederal University of Ceará, School of Medicine, Division of Nephrology, Department of Internal Medicine. Fortaleza, CE, Brazil. E-mails: leonardo.luna@hotmail.com; douglas.sousa.soares@gmail.com; lara.raissa@gmail.com; ef.daher@uol.com.br.
Geraldo Bezerra da Silva JuniorUniversity of Fortaleza, School of Medicine, Public Health Graduate Program. Fortaleza, CE, Brazil. E-mails: geraldobezerrajr@yahoo.com.br; eanes@fortalnet.com.br; ef.daher@uol.com.br.
Malena Gadelha CavalcanteFederal University of Ceará, School of Medicine, Medical Sciences and Pharmacology Graduate Program. Fortaleza, CE, Brazil. E-mails: malenagadelha@hotmail.com; gdayllon@yahoo.com.br.
Lara Raissa Cavalcante MalveiraFederal University of Ceará, School of Medicine, Division of Nephrology, Department of Internal Medicine. Fortaleza, CE, Brazil. E-mails: leonardo.luna@hotmail.com; douglas.sousa.soares@gmail.com; lara.raissa@gmail.com; ef.daher@uol.com.br.
Gdayllon Cavalcante MenesesFederal University of Ceará, School of Medicine, Medical Sciences and Pharmacology Graduate Program. Fortaleza, CE, Brazil. E-mails: malenagadelha@hotmail.com; gdayllon@yahoo.com.br.
Eanes Delgado Barros PereiraUniversity of Fortaleza, School of Medicine, Public Health Graduate Program. Fortaleza, CE, Brazil. E-mails: geraldobezerrajr@yahoo.com.br; eanes@fortalnet.com.br; ef.daher@uol.com.br.
Elizabeth De Francesco DaherFederal University of Ceará, School of Medicine, Division of Nephrology, Department of Internal Medicine. Fortaleza, CE, Brazil. E-mails: leonardo.luna@hotmail.com; douglas.sousa.soares@gmail.com; lara.raissa@gmail.com; ef.daher@uol.com.br.
Universidade Federal do Ceará · BRUniversidade de Fortaleza · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study is to describe clinical characteristics, outcomes and risk factors for death among patients with HIV-related acute kidney injury (AKI) admitted to an intensive care unit (ICU).

methodsA retrospective study was conducted with HIV-infected AKI patients admitted to the ICU of an infectious diseases hospital in Fortaleza, Brazil. All the patients with confirmed diagnosis of HIV and AKI admitted from January 2004 to December 2011 were included. A comparison between survivors and non-survivors was performed. Risk factors for death were investigated.

resultsAmong 256 AKI patients admitted to the ICU in the study period, 73 were identified as HIV-infected, with a predominance of male patients (83.6%), and the mean age was 41.2 ± 10.4 years. Non-survivor patients presented higher APACHE II scores (61.4 ± 19 vs. 38.6 ± 18, p = 0.004), used more vasoconstrictors (70.9 vs. 37.5%, p = 0.02) and needed more mechanical ventilation - MV (81.1 vs. 35.3%, p = 0.001). There were 55 deaths (75.3%), most of them (53.4%) due to septic shock. Independent risk factors for mortality were septic shock (OR = 14.2, 95% CI = 2.0-96.9, p = 0.007) and respiratory insufficiency with need of MV (OR = 27.6, 95% CI = 5.0-153.0, p < 0.001).

conclusionNon-survivor HIV-infected patients with AKI admitted to the ICU presented higher severity APACHE II scores, more respiratory damage and hemodynamic impairment than survivors. Septic shock and respiratory insufficiency were independently associated to death.

Indexed as

Critical IllnessAcute Kidney InjuryAdultCause of DeathFemaleHIV InfectionsHumansIntensive Care UnitsMaleRetrospective StudiesRisk FactorsTreatment Outcome

Identifiers

PMID27410912
PMCPMC4964321
OpenAlexW2468224822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.