Evidence map›Paper›PMID 27410411›Full record

Observational studyRevista Brasileira de terapia intensiva2016

Atrial natriuretic factor: is it responsible for hyponatremia and natriuresis in neurosurgery?

Ana Paula Devite Cardoso Gasparotto, Antonio Luis Eiras Falcão, Carolina Kosour, Sebastião Araújo, Eliane Araújo Cintra, Rosmari Aparecida Rosa Almeida de Oliveira, Luiz Claudio Martins, Desanka Dragosavac

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Revista Brasileira de terapia intensiva, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana Paula Devite Cardoso GasparottoDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Antonio Luis Eiras FalcãoDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Carolina KosourDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Sebastião AraújoDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Eliane Araújo CintraDepartamento de Enfermagem, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Rosmari Aparecida Rosa Almeida de OliveiraDepartamento de Fisioterapia, Pontifícia Universidade Católica de Campinas, Campinas, SP, Brazil.
Luiz Claudio MartinsDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Desanka DragosavacDepartamento de Cirurgia, Faculdade de Medicina, Universidade Estadual de Campinas, Campinas, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the presence of hyponatremia and natriuresis and their association with atrial natriuretic factor in neurosurgery patients.

methodsThe study included 30 patients who had been submitted to intracranial tumor resection and cerebral aneurism clipping. Both plasma and urinary sodium and plasma atrial natriuretic factor were measured during the preoperative and postoperative time periods.

resultsHyponatremia was present in 63.33% of the patients, particularly on the first postoperative day. Natriuresis was present in 93.33% of the patients, particularly on the second postoperative day. Plasma atrial natriuretic factor was increased in 92.60% of the patients in at least one of the postoperative days; however, there was no statistically significant association between the atrial natriuretic factor and plasma sodium and between the atrial natriuretic factor and urinary sodium.

conclusionHyponatremia and natriuresis were present in most patients after neurosurgery; however, the atrial natriuretic factor cannot be considered to be directly responsible for these alterations in neurosurgery patients. Other natriuretic factors are likely to be involved.

Indexed as

AdultAtrial Natriuretic FactorBrain NeoplasmsFemaleHumansHyponatremiaIntracranial AneurysmMaleMiddle AgedNatriuresisNeurosurgical ProceduresPostoperative PeriodPreoperative PeriodProspective StudiesSodiumAtrial Natriuretic FactorSodium

Identifiers

PMID27410411
PMCPMC4943053

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.