Evidence map›Paper›PMID 27410039›Full record

ArticlePLoS neglected tropical diseases2016

Geographic Distribution of Leishmania Species in Ecuador Based on the Cytochrome B Gene Sequence Analysis.

Hirotomo Kato, Eduardo A Gomez, Luiggi Martini-Robles, Jenny Muzzio, Lenin Velez, Manuel Calvopiña, Daniel Romero-Alvarez, Tatsuyuki Mimori, Hiroshi Uezato, Yoshihisa Hashiguchi

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. An Update on Clinical and Pathogenic Spectra of Leishmaniasis.Expert reviews in molecular medicine · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genetic diversity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  9. Prevalence of Genetically ComplexFrontiers in cellular and infection microbiology · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The study ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hirotomo KatoDivision of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan.
Eduardo A GomezDepartamento de Parasitologia y Medicina Tropical, Facultad de Ciencias Medicas, Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuador.
Luiggi Martini-RoblesDepartamento de Parasitologia, Insitituto de Investigacion de Salud Publica, Guayaquil, Ecuador.
Jenny MuzzioDepartamento de Parasitologia, Insitituto de Investigacion de Salud Publica, Guayaquil, Ecuador.
Lenin VelezDepartamento de Parasitologia y Medicina Tropical, Facultad de Ciencias Medicas, Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuador.
Manuel CalvopiñaCentro de Biomedicina, Facultad de Medicina, Universidad Central del Ecuador, Quito, Ecuador.
Daniel Romero-AlvarezCentro de Biomedicina, Facultad de Medicina, Universidad Central del Ecuador, Quito, Ecuador.
Tatsuyuki MimoriDepartment of Microbiology, Faculty of Life Sciences, Graduate School of Health Sciences, Kumamoto University, Kumamoto, Japan.
Hiroshi UezatoDepartment of Dermatology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Yoshihisa HashiguchiDepartamento de Parasitologia y Medicina Tropical, Facultad de Ciencias Medicas, Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A countrywide epidemiological study was performed to elucidate the current geographic distribution of causative species of cutaneous leishmaniasis (CL) in Ecuador by using FTA card-spotted samples and smear slides as DNA sources. Putative Leishmania in 165 samples collected from patients with CL in 16 provinces of Ecuador were examined at the species level based on the cytochrome b gene sequence analysis. Of these, 125 samples were successfully identified as Leishmania (Viannia) guyanensis, L. (V.) braziliensis, L. (V.) naiffi, L. (V.) lainsoni, and L. (Leishmania) mexicana. Two dominant species, L. (V.) guyanensis and L. (V.) braziliensis, were widely distributed in Pacific coast subtropical and Amazonian tropical areas, respectively. Recently reported L. (V.) naiffi and L. (V.) lainsoni were identified in Amazonian areas, and L. (L.) mexicana was identified in an Andean highland area. Importantly, the present study demonstrated that cases of L. (V.) braziliensis infection are increasing in Pacific coast areas.

Indexed as

Cytochromes bEcuadorGene Expression RegulationHumansLeishmaniaLeishmaniasisPhylogenyCytochromes b

Identifiers

PMID27410039
PMCPMC4943627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.