Evidence map›Paper›PMID 27409483›Full record

ReviewInvestigative ophthalmology & visual science2016

Optical Coherence Tomography Angiography.

Simon S Gao, Yali Jia, Miao Zhang, Johnny P Su, Gangjun Liu, Thomas S Hwang, Steven T Bailey, David Huang

Open access · goldAbstract readReview
In one paragraph

Review in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed, 3 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

193 citing papers in PubMed, 3 syntheses or guidelines pooled it, 345 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Central retinal artery occlusion: meta-analysis of the risk of new-onset atrial fibrillation and ischemic stroke.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  7. Preclinical in-vivo cerebrovascular imaging in rodent models: Methods and applications in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  8. Article
  9. Anti-VEGF therapy for symptomatic exudative retinal arterial macroaneurysms: functional and anatomic outcomes with OCTA findings.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Observational
  17. Review
  18. Article
  19. Article
  20. Observational

133 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Simon S Gao
Yali Jia
Miao Zhang
Johnny P Su
Gangjun Liu
Thomas S Hwang
Steven T Bailey
David Huang
Oregon Health & Science University · US

Funding

Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
Functional and Structural Optical Coherence Tomography for GlaucomaR01EY023285 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2013 to 2026
$8.8M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
Guiding the Treatment of Anterior Eye Disease with Optical Coherence TomographyR01EY018184 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HUANG, DAVID · 2008 to 2015
$4.9M
Translational Vision Science Research at Oregon Health & Science UniversityT32EY023211 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Yali Jia, Kate E Keller · 2013 to 2026
$2.4M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
NCATS NIH HHS UL1 TR000128NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY018184NEI NIH HHS R01 EY023285NEI NIH HHS R01 EY024544NEI NIH HHS T32 EY023211NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

Optical coherence tomography angiography (OCTA) is a noninvasive approach that can visualize blood vessels down to the capillary level. With the advent of high-speed OCT and efficient algorithms, practical OCTA of ocular circulation is now available to ophthalmologists. Clinical investigations that used OCTA have increased exponentially in the past few years. This review will cover the history of OCTA and survey its most important clinical applications. The salient problems in the interpretation and analysis of OCTA are described, and recent advances are highlighted.

Indexed as

CapillariesChoroidal NeovascularizationFluorescein AngiographyFundus OculiHumansRetinal VesselsTomography, Optical Coherence

Identifiers

PMID27409483
PMCPMC4968919
OpenAlexW2462081900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.