ArticleInvestigative ophthalmology & visual science2016
Posterior Eye Shape Measurement With Retinal OCT Compared to MRI.
Article in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
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- Asymmetry between nasal and temporal refraction with accommodation in myopes and emmetropes.Biomedical optics express · 2026Article
- Article
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- Effect of Deep Optic Nerve Head Morphology on Lamina Cribrosa and Peripapillary Scleral Configurations in Healthy Eyes.Investigative ophthalmology & visual science · 2025Article
- Three-Dimensional Choroidal Contour Mapping in Healthy and Diseased Eyes.Translational vision science & technology · 2025Article
- Intraoperative adaptive eye model based on instrument-integrated OCT for robot-assisted vitreoretinal surgery.International journal of computer assisted radiology and surgery · 2025Article
- Thinning Choroidal Thickness and Flattening Morphology of Higher Myopia Eyes in Chinese Adults with Anisometropic Myopia: A Comparative Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Retinal and cerebral hemodynamics redistribute to favor thermoregulation in response to passive environmental heating and heated exercise in humans.Temperature (Austin, Tex.) · 2025Article
- Distortion-Corrected Posterior Ocular Shape in Myopic Eyes Assessed by Ultrawide OCT Detects Deformations Associated With Vision-Threatening Changes.Investigative ophthalmology & visual science · 2024Observational
- Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature.Investigative ophthalmology & visual science · 2024Article
- Impact of Genetic and Environmental Factors on Peripheral Refraction.Translational vision science & technology · 2024Article
- Assessment of OCT-Based Macular Curvature and Its Relationship with Macular Microvasculature in Children with Anisomyopia.Ophthalmology and therapy · 2024Article
- Are Macula or Optic Nerve Head Structures Better at Diagnosing Glaucoma? An Answer Using Artificial Intelligence and Wide-Field Optical Coherence Tomography.Translational vision science & technology · 2024Article
- Ocular Deformations in Spaceflight-Associated Neuro-Ocular Syndrome and Idiopathic Intracranial Hypertension.Investigative ophthalmology & visual science · 2023Article
- Regional differences of the sclera in the ocular hypertensive rat model induced by circumlimbal suture.Eye and vision (London, England) · 2023Article
- Analysis of morphological and quantitative changes in pathological myopia and perioperative changes in posterior scleral reinforcement using three-dimensional magnet resonance imaging.Frontiers in bioengineering and biotechnology · 2023Article
- Automated Classification and Detection of Staphyloma with Ultrasound Images in Pathologic Myopia Eyes.Ultrasound in medicine & biology · 2022Article
- Radial and Tangential Retinal Magnifications as Functions of Visual Field Angle Across Spherical, Oblate, and Prolate Retinal Profiles.Translational vision science & technology · 2022Article
- Quantification and Predictors of OCT-Based Macular Curvature and Dome-Shaped Configuration: Results From the UK Biobank.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
purposePosterior eye shape assessment by magnetic resonance imaging (MRI) is used to study myopia. We tested the hypothesis that optical coherence tomography (OCT), as an alternative, could measure posterior eye shape similarly to MRI.
methodsMacular spectral-domain OCT and brain MRI images previously acquired as part of the Singapore Epidemiology of Eye Diseases study were analyzed. The right eye in the MRI and OCT images was automatically segmented. Optical coherence tomography segmentations were corrected for optical and display distortions requiring biometry data. The segmentations were fitted to spheres and ellipsoids to obtain the posterior eye radius of curvature (Rc) and asphericity (Qxz). The differences in Rc and Qxz measured by MRI and OCT were tested using paired t-tests. Categorical assignments of prolateness or oblateness using Qxz were compared.
resultsFifty-two subjects (67.8 ± 5.6 years old) with spherical equivalent refraction from +0.50 to -5.38 were included. The mean paired difference between MRI and original OCT posterior eye Rc was 24.03 ± 46.49 mm (P = 0.0005). For corrected OCT images, the difference in Rc decreased to -0.23 ± 2.47 mm (P = 0.51). The difference between MRI and OCT asphericity, Qxz, was -0.052 ± 0.343 (P = 0.28). However, categorical agreement was only moderate (κ = 0.50).
conclusionsDistortion-corrected OCT measurements of Rc and Qxz were not statistically significantly different from MRI, although the moderate categorical agreement suggests that individual differences remained. This study provides evidence that with distortion correction, noninvasive office-based OCT could potentially be used instead of MRI for the study of posterior eye shape.
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