Evidence map›Paper›PMID 27409078›Full record

SynthesisPloS one2016

A Meta-Analysis and Systematic Review on the Association between Human Papillomavirus (Types 16 and 18) Infection and Esophageal Cancer Worldwide.

Jing Wang, Lei Zhao, Han Yan, Juanjuan Che, Li Huihui, Wu Jun, Bing Liu, Bangwei Cao

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Oral Alpha, Beta, and Gamma HPV Types and Risk of Incident Esophageal Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018
    Article
  15. Human Gut Microbiota and Gastrointestinal Cancer.Genomics, proteomics & bioinformatics · 2018
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing WangDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Lei ZhaoDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Han YanDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Juanjuan CheDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Li HuihuiDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Wu JunDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Bing LiuDepartment of Emergency, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Bangwei CaoDepartment of Oncology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal cancer is a common and aggressive malignant tumor. This study aimed to investigate the association between human papillomavirus (HPV) Types 16 and 18 and esophageal carcinoma (EC) in the world population by conducting a meta-analysis. MATERIALS AND

methodsComputerized bibliographic and manual searches were performed to identify all eligible literatures between 1982 and 2014. PUBMED (http://www.ncbi.nlm.nih.gov/pubmed/) and CNKI (http://www.cnki.net/) were the primary sources of case-control studies, and key words used include human papillomavirus, HPV, esophageal, esophagus, cancer, carcinoma, and tumor. All searches were performed by reviewing articles and abstracts cited in the published systematic reviews and case-control studies. Prospective studies that reported relative risk (RR) estimates with 95% CIs for the association between HPV and EC were included.

resultsThirty-three randomized studies were identified, and the main features of these trials were included in this systematic review. HPV infection rate in the EC group was 46.5%, while HPV infection rate in the control group was 26.2% (OR = 1.62; 95% CI, 1.33-1.98). In China, the merger OR value was 1.62 (95% CI: 1.26-2.07); while in the Asian region, the merger OR value was 1.63 (95% CI: 1.29-2.04). There were statistical differences in HPV testing due to different detection methods such as PCR, IHC and ISH. In the PCR detection group, the merger OR value was 1.61 (95% CI: 1.33-1.95).

conclusionsThese results indicate that HPV infection and the incidence of EC are closely associated.

Indexed as

InternationalityEsophageal NeoplasmsHuman papillomavirus 16Human papillomavirus 18Humans

Identifiers

PMID27409078
PMCPMC4943681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.