Evidence map›Paper›PMID 27408912›Full record

ArticleData in brief2016

Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect.

Nikola Kovářová, Petr Pecina, Hana Nůsková, Marek Vrbacký, Massimo Zeviani, Tomáš Mráček, Carlo Viscomi, Josef Houštěk

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Tissue- and Condition-Specific Isoforms of Mammalian CytochromeOxidative medicine and cellular longevity · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Nikola KovářováInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Petr PecinaInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Hana NůskováInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Marek VrbackýInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Massimo ZevianiMolecular Neurogenetics Unit, Instituto Neurologico "C. Besta", via Temolo 4, 20126 Milan, Italy; MRC-Mitochondrial Biology Unit, Wellcome Trust MRC Bldg, Addenbrookes Hospital Hills Rd, Cambridge CB2 0XY, UK.
Tomáš MráčekInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Carlo ViscomiMRC-Mitochondrial Biology Unit, Wellcome Trust MRC Bldg, Addenbrookes Hospital Hills Rd, Cambridge CB2 0XY, UK.
Josef HouštěkInstitute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Czech Academy of Sciences · CZCzech Academy of Sciences, Institute of Physiology · CZMRC Mitochondrial Biology Unit · GB

Funding

Medical Research Council MC_UP_1002/1
6 · The paper itself

Abstract

This paper describes data related to a research article entitled "Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects" [1]. This paper includes data of the quantitative analysis of individual forms of respiratory chain complexes I, III and IV present in SURF1 knockout (SURF1 (-/-) ) and control (SURF1 (+/+) ) mouse fibroblasts and tissues and in fibroblasts of human control and patients with SURF1 gene mutation. Also it includes data demonstrating response of complex IV, cytochrome c oxidase (COX), to reversible inhibition of mitochondrial translation in SURF1 (-/-) mouse and SURF1 patient fibroblast cell lines.

Indexed as

COX, Cytochrome c oxidaseCytochrome c oxidaseDOX, doxycyclineDoxycyclineKnockoutRespiratory chainSURF1

Identifiers

PMID27408912
PMCPMC4927972
OpenAlexW2310505594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.