Evidence map›Paper›PMID 27408870›Full record

ArticleAsia Oceania journal of nuclear medicine & biology2014

Radionuclide Treatment with 153Sm-EDTMP is Effective for the Palliation of Bone Pain in the Context of Extensive Bone Marrow Metastases: A Case Report.

Kalevi Kairemo, Nigora Rasulova, Justina Suslaviciute, Tuomo Alanko

Open access · greenAbstract readCase Reports
In one paragraph

Article in Asia Oceania journal of nuclear medicine & biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kalevi KairemoDepartment of Molecular Radiotherapy & Nuclear Medicine, Docrates Cancer Center, Helsinki, Finland.
Nigora RasulovaDepartment of Molecular Radiotherapy & Nuclear Medicine, Docrates Cancer Center, Helsinki, Finland.
Justina SuslaviciuteDepartment of Medical Oncology, Docrates Cancer Center, Helsinki, Finland.
Tuomo AlankoDepartment of Medical Oncology, Docrates Cancer Center, Helsinki, Finland.
Docrates Cancer Center · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radionuclide therapy is widely used as an effective modality in the management of bone pain. The main indication for this treatment is symptomatic bone metastases, confirmed by bone scintigraphy. We present a case of small cell lung cancer (SCLC) stage T4N2M1b, with a good metabolic response to systemic therapy and radiotherapy of the primary tumor and locoregional disease, which became metabolically less active and remarkably smaller in size (reduction to 1/6 of the original volume). In spite of the good overall response, the patient developed a syndrome with severe bone pain and had progression in the bone marrow metastases, confirmed by (18)F-FDG PET/CT. The patient received (153)Sm-EDTMP treatment with a good clinical response. However, in the whole body bone scan with the therapeutic dose, there was no visual evidence of bone metastasis. Retrospectively, by drawing the region of interest, it was possible to identify one metastatic site. The possible mechanisms of the efficacy of this treatment modality, in this specific setting, are also discussed.

Indexed as

153Sm-EDTMPBone marrow metastasesBone metastasesPositron emission tomography (PET)Radionuclide therapySmall cell lung cancer

Identifiers

PMID27408870
PMCPMC4937698
OpenAlexW2270181705

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.